DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBM4 and ssx

DIOPT Version :9

Sequence 1:	NP_002887.2	Gene:	RBM4 / 5936	HGNCID:	9901	Length:	364	Species:	Homo sapiens
Sequence 2:	NP_569908.1	Gene:	ssx / 31086	FlyBaseID:	FBgn0024987	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	45/153 - (29%)
Similarity:	81/153 - (52%)	Gaps:	18/153 - (11%)

- Green bases have known domain annotations that are detailed below.

Human     4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNLHHYKL 60
            |.|..||::.|::|:.:||...|.:..|.|:::        ||||..:.::.:||||:.|:.:.:
  Fly    95 LIINYLPQDMTDRELYNLFSGCGPINTCKIMRDFKTGYSFGYGFVDYKTESDSEDAIQKLNGFYV 159

Human    61 HGVNINVEASK--NKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKD--------YAF 115
            ....:.|..::  .:|...|.|:|.|:|....:..|...|..||.:::.:|::|        .||
  Fly   160 RNKRLKVSYARPGGQSIKDTNLYVINLSRNINDDMLDRIFSPYGLIVQRNILRDKLTGRPRGVAF 224

Human   116 VHMERAEDAVEAIRGLDNTEFQG 138
            |...:.|:|.|||:.|:||..:|
  Fly   225 VRYNKREEAQEAIKALNNTVPEG 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM4	NP_002887.2	RRM1_RBM4	2..68	CDD:410018	20/71 (28%)
		RRM2_RBM4	78..144	CDD:410019	23/69 (33%)
		PTZ00368	<145..>181	CDD:173561
		ZnF_C2HC	161..176	CDD:197667
		Interaction with TNPO3. /evidence=ECO:0000269\|PubMed:12628928	196..364
ssx	NP_569908.1	RRM_SF	93..173	CDD:302621	21/77 (27%)
ssx	NP_569908.1	RRM_SF	179..257	CDD:302621	23/69 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910