DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBM3 and cirbpa

DIOPT Version :9

Sequence 1:	NP_006734.1	Gene:	RBM3 / 5935	HGNCID:	9900	Length:	157	Species:	Homo sapiens
Sequence 2:	NP_001017797.1	Gene:	cirbpa / 550495	ZFINID:	ZDB-GENE-050417-329	Length:	185	Species:	Danio rerio

Alignment Length:	184	Identity:	86/184 - (46%)
Similarity:	106/184 - (57%)	Gaps:	34/184 - (18%)

- Green bases have known domain annotations that are detailed below.

Human     3 SEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASVAMRAM 67
            |:|||||:|||:|:|.||:|||.||.:|.|:.|.|.::|||.|||||||:||.||:.|..|:..|
Zfish     2 SDEGKLFIGGLSFDTTEQSLEDAFSKYGVITNVHVARNRETNRSRGFGFVTFENPDDAKDALEGM 66

Human    68 NGESLDGRQIRVDHAGKSARGTRGGGFGAHGRGRSYSRGGGDQGYGSGRYYDSR---PGGYGYGY 129
            ||:|:|||.||||.|||..    |||.|..|.|.||..|||.:|.|.|.:...|   .||.|||
Zfish    67 NGKSVDGRTIRVDEAGKGG----GGGGGRSGGGGSYRGGGGGRGGGGGFFRGGRGRGGGGGGYG- 126

Human   130 GRSRDYNGRNQGG---------------------YDRYSG-----GNYRDNYDN 157
            |..|.|..|:.||                     .||.||     .:|:|.||:
Zfish   127 GGDRSYGDRSYGGGGGGYKSGGGGYSSGGGGGYNRDRGSGYGDRSSSYKDGYDS 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM3	NP_006734.1	RRM_CIRBP_RBM3	6..85	CDD:409883	49/78 (63%)
RBM3	NP_006734.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..157		36/104 (35%)
cirbpa	NP_001017797.1	RRM	<2..>81	CDD:223796	49/78 (63%)
cirbpa	NP_001017797.1	RRM_SF	5..83	CDD:302621	48/77 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG43500
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000446
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100265
Panther	1	1.100	-	-	O	PTHR48034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920