DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBM3 and cirbp

DIOPT Version :9

Sequence 1:	NP_006734.1	Gene:	RBM3 / 5935	HGNCID:	9900	Length:	157	Species:	Homo sapiens
Sequence 2:	NP_001017228.1	Gene:	cirbp / 549982	XenbaseID:	XB-GENE-492781	Length:	166	Species:	Xenopus tropicalis

Alignment Length:	166	Identity:	97/166 - (58%)
Similarity:	117/166 - (70%)	Gaps:	14/166 - (8%)

- Green bases have known domain annotations that are detailed below.

Human     1 MSSEEGKLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPEHASVAMR 65
            ||.:|||||||||||.|.|::||..||.:|.::|||||||||::|||||||:||.|||.|..||.
Frog     1 MSCDEGKLFVGGLNFETTEESLEQVFSKYGQVAEVVVVKDRESKRSRGFGFVTFENPEDAKDAMM 65

Human    66 AMNGESLDGRQIRVDHAGKSARGTRGG---------GFGAHGRGRSYSRGGGDQGYGSGRYYDSR 121
            ||||:|:||||||||.||||:...|||         ||...||||.   ||||:|||....:::|
Frog    66 AMNGKSVDGRQIRVDQAGKSSNDRRGGYRGGSSGGRGFFRGGRGRG---GGGDRGYGGSSRFENR 127

Human   122 PGGYGYGYGRSRDYNGRNQGGYDRYSGGNYRDNYDN 157
            .|  ||....||||.||:.|.|...|||:|||:||:
Frog   128 SG--GYQSSGSRDYYGRSHGSYGDRSGGSYRDSYDS 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM3	NP_006734.1	RRM_CIRBP_RBM3	6..85	CDD:409883	56/78 (72%)
RBM3	NP_006734.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..157		39/84 (46%)
cirbp	NP_001017228.1	RRM_CIRBP_RBM3	6..85	CDD:409883	56/78 (72%)
cirbp	NP_001017228.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	68..166		51/99 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG43500
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000446
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48034
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020