DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RBM3 and Hrb87F

DIOPT Version :9

Sequence 1:	NP_006734.1	Gene:	RBM3 / 5935	HGNCID:	9900	Length:	157	Species:	Homo sapiens
Sequence 2:	NP_001163602.1	Gene:	Hrb87F / 48535	FlyBaseID:	FBgn0004237	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	227	Identity:	65/227 - (28%)
Similarity:	87/227 - (38%)	Gaps:	82/227 - (36%)

- Green bases have known domain annotations that are detailed below.

Human     7 KLFVGGLNFNTDEQALEDHFSSFGPISEVVVVKDRETQRSRGFGFITFTNPE----------HA- 60
            |||||||..:.||:.|.::|..||.|..|.:|.|::|.:.|||.||.|.:.:          |:
  Fly   116 KLFVGGLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSI 180

Human    61 ---------SVAMRAMN---------GESLDGRQIRVDHAGKSARGTRGGGFGAHGR-------- 99
                     ::|.:.|:         |....||      .|:..||..|||:|...|
  Fly   181 KNKTLDVKKAIAKQDMDRQGGGGGRGGPRAGGR------GGQGDRGQGGGGWGGQNRQNGGGNWG 239

Human   100 --------GRSYSRGGGDQGYGSGRYYD-------------------SRPGGYGYGYGRSRDYNG 137
                    |.|....||.||.|||.:..                   :..||.|||.|.|....|
  Fly   240 GAGGGGGFGNSGGNFGGGQGGGSGGWNQQGGSGGGPWNNQGGGNGGWNGGGGGGYGGGNSNGSWG 304

Human   138 RNQGG----------YDR-YSGGNYRD-NYDN 157
            .|.||          |.: |.||..|: |:.|
  Fly   305 GNGGGGGGGGGFGNEYQQSYGGGPQRNSNFGN 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RBM3	NP_006734.1	RRM_CIRBP_RBM3	6..85	CDD:409883	31/106 (29%)
RBM3	NP_006734.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	81..157		34/122 (28%)
Hrb87F	NP_001163602.1	RRM1_hnRNPA_like	25..102	CDD:241022
Hrb87F	NP_001163602.1	RRM_SF	116..188	CDD:302621	25/71 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910