Protein Alignment PRDM12 and prdm12

DIOPT Version :10

• Sequence 1: NP_067632.2
• Gene: PRDM12 / 59335
• HGNCID: 13997
• Length: 367
• Species: Homo sapiens
• Sequence 2: NP_001072898.1
• Gene: prdm12 / 780360
• XenbaseID: XB-GENE-953729
• Length: 354
• Species: Xenopus tropicalis
• Alignment Length: 367
• Identity: 314/367 - (85%)
• Similarity: 330/367 - (89%)
• Gaps: 13/367 - (3%)

Human     1 MMGSVLPAEALVLKTGLKAPGLALAEVITSDILHSFLYGRWRNVLGEQLFEDKSHHASPKTAFTA 65
            ||||||||||||||.|||.|||:|||:||||||||||||||||||||||||:|::|:||||||||
 Frog     1 MMGSVLPAEALVLKGGLKQPGLSLAELITSDILHSFLYGRWRNVLGEQLFEEKNNHSSPKTAFTA 65

Human    66 EVLAQSFSGEVQKLSSLVLPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVIAPEHVDIC 130
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||:|||||:|
 Frog    66 EVLAQSFSGEVQKLSSLVLPSEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVISPEHVDLC 130

Human   131 KNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPD 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||.|.||||.|.||||
 Frog   131 KNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGNSTFYKATETIPPD 195

Human   196 QELLVWYGNSHNTFLGIPGVPGLEEDQKKNKHEDFHPADSAAGPAGRMRCVICHRGFNSRSNLRS 260
            |||||||||..|||||||||||:||:|||:|||:|...|......||||||||||||||||||||
 Frog   196 QELLVWYGNFPNTFLGIPGVPGMEEEQKKSKHEEFGSVDVVPTMTGRMRCVICHRGFNSRSNLRS 260

Human   261 HMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCQVCQSAYSQLAGLRAHQKSARHRP 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   261 HMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCQVCQSAYSQLAGLRAHQKSARHRP 325

Human   326 PSTALQAHSPALPAPHAHAPALAAAAAAAAAAAAHHLPAMVL 367
            |:.:||||||.||.||             .|..|||:|.|||
 Frog   326 PNNSLQAHSPTLPVPH-------------PATLAHHIPTMVL 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRDM12	NP_067632.2	PR-SET_PRDM12	84..213	CDD:380973	119/128 (93%)
		zf-C2H2	244..265	CDD:395048	20/20 (100%)
		C2H2 Zn finger	245..265	CDD:275368	19/19 (100%)
		zf-H2C2_2	257..282	CDD:463886	24/24 (100%)
		C2H2 Zn finger	273..293	CDD:275368	19/19 (100%)
		zf-H2C2_2	286..310	CDD:463886	23/23 (100%)
		C2H2 Zn finger	301..319	CDD:275368	17/17 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..337		15/18 (83%)
prdm12	NP_001072898.1	PR-SET_PRDM12	84..213	CDD:380973	119/128 (93%)
		zf-C2H2	244..265	CDD:395048	20/20 (100%)
		C2H2 Zn finger	245..265	CDD:275368	19/19 (100%)
		zf-H2C2_2	257..282	CDD:463886	24/24 (100%)
		C2H2 Zn finger	273..293	CDD:275368	19/19 (100%)
		zf-H2C2_2	286..310	CDD:463886	23/23 (100%)
		C2H2 Zn finger	301..319	CDD:275368	17/17 (100%)