Protein Alignment PRDM12 and prdm12b

DIOPT Version :10

• Sequence 1: NP_067632.2
• Gene: PRDM12 / 59335
• HGNCID: 13997
• Length: 367
• Species: Homo sapiens
• Sequence 2: XP_073806363.1
• Gene: prdm12b / 492816
• ZFINID: ZDB-GENE-041114-172
• Length: 483
• Species: Danio rerio
• Alignment Length: 380
• Identity: 305/380 - (80%)
• Similarity: 324/380 - (85%)
• Gaps: 26/380 - (6%)

Human     1 MMGSVLPAEALVLKTGLKAPGLALAEVITSDILHSFLYGRWRNVLGEQLFEDKSHHASPKTAFTA 65
            :|||||||:|||||.|.|...|||:::||||||||||||||||||||.|||:|:...||||||||
Zfish   117 IMGSVLPADALVLKAGFKQQSLALSDIITSDILHSFLYGRWRNVLGEHLFEEKTATVSPKTAFTA 181

Human    66 EVLAQSFSGEVQKLSSLVLPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVIAPEHVDIC 130
            ||||||||||||||||||||:||||||||||||||||||||||||||||||||||||:|||||:.
Zfish   182 EVLAQSFSGEVQKLSSLVLPSEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVISPEHVDLF 246

Human   131 KNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPD 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||:||||||:|.||||
Zfish   247 KNNNLMWEVFNEDGTVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGSSIFYKAVETIPPD 311

Human   196 QELLVWYGNSHNTFLGIPGVPGLEED-QKKNKHEDFHPAD----SAAGPAGRMRCVICHRGFNSR 255
            ||||||||||||||||||||||.||: |||.|.::||..|    :|...|.||||||||||||||
Zfish   312 QELLVWYGNSHNTFLGIPGVPGTEEEQQKKTKTDEFHLCDTVTAAALSTASRMRCVICHRGFNSR 376

Human   256 SNLRSHMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCQVCQSAYSQLAGLRAHQKS 320
            ||||||||||||||||||||||||||||||||||||||||||||||.||||||||||||||||||
Zfish   377 SNLRSHMRIHTLDKPFVCRFCNRRFSQSSTLRNHVRLHTGERPYKCHVCQSAYSQLAGLRAHQKS 441

Human   321 ARHRPPST----ALQAHSPALP----APHAHAPALAAAAAAAAAAAAHHLPAMVL 367
            |||||.:|    .||||||..|    .||             .|:..||:|.|||
Zfish   442 ARHRPANTGAVVGLQAHSPPPPQLAQVPH-------------PASLVHHIPTMVL 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRDM12	NP_067632.2	PR-SET_PRDM12	84..213	CDD:380973	121/128 (95%)
		zf-C2H2	244..265	CDD:395048	20/20 (100%)
		C2H2 Zn finger	245..265	CDD:275368	19/19 (100%)
		zf-H2C2_2	257..282	CDD:463886	24/24 (100%)
		C2H2 Zn finger	273..293	CDD:275368	19/19 (100%)
		zf-H2C2_2	286..310	CDD:463886	22/23 (96%)
		C2H2 Zn finger	301..319	CDD:275368	16/17 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	318..337		15/22 (68%)
prdm12b	XP_073806363.1	None