DRSC/TRiP Functional Genomics Resources

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Protein Alignment PRDM12 and set-17

DIOPT Version :10

Sequence 1:NP_067632.2 Gene:PRDM12 / 59335 HGNCID:13997 Length:367 Species:Homo sapiens
Sequence 2:NP_001317778.1 Gene:set-17 / 174425 WormBaseID:WBGene00011887 Length:277 Species:Caenorhabditis elegans


Alignment Length:150 Identity:51/150 - (34%)
Similarity:77/150 - (51%) Gaps:14/150 - (9%)


- Green bases have known domain annotations that are detailed below.


Human    80 SSLVLPAEVIIAQSSIPGEGLGIFSKTWIKAGTEMGPFTGRVIAPEHVDICKNNNLMWEVFNEDG 144
            |...||....|.:|.:|..|||:.::.:|..|...||:.|| ...:..|..| :...|.:  :.|
 Worm   127 SQQTLPILFRIEESKLPNAGLGVIAEVFIPVGMVFGPYKGR-RCQKKTDFYK-DGYAWLI--KSG 187

Human   145 TVRYFIDASQEDHRSWMTYIKCARNEQEQNLEVVQIGTSIFYKAIEMIPPDQELLVWYGNSH-NT 208
            ..|::||.|..:..:|:.||...|.|.|||:...|....|||:.|:.|..:||||||||:|: |.
 Worm   188 DKRFYIDGSDAERSNWLRYINSPRFEDEQNMLAFQTNGKIFYRVIKPIRINQELLVWYGSSYGNE 252

Human   209 FLGIPGVPGLEEDQKKNKHE 228
            |:         |.:..||::
 Worm   253 FV---------ESENGNKYK 263

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PRDM12NP_067632.2 PR-SET_PRDM12 84..213 CDD:380973 47/129 (36%)
zf-C2H2 244..265 CDD:395048
C2H2 Zn finger 245..265 CDD:275368
zf-H2C2_2 257..282 CDD:463886
C2H2 Zn finger 273..293 CDD:275368
zf-H2C2_2 286..310 CDD:463886
C2H2 Zn finger 301..319 CDD:275368
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 318..337
set-17NP_001317778.1 PHD_SF 82..>113 CDD:473978
PR-SET_PRDM7_9 128..255 CDD:380970 47/139 (34%)
Blue background indicates that the domain is not in the aligned region.

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