Protein Alignment RBBP7 and HAT2

DIOPT Version :10

• Sequence 1: XP_047298247.1
• Gene: RBBP7 / 5931
• HGNCID: 9890
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_010858.3
• Gene: HAT2 / 856654
• SGDID: S000000782
• Length: 401
• Species: Saccharomyces cerevisiae
• Alignment Length: 454
• Identity: 150/454 - (33%)
• Similarity: 228/454 - (50%)
• Gaps: 94/454 - (20%)

Human    60 INEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHTS-DEQNHLV 123
            ::|||.:||.|.|.:||.|....|.||||||||||...:.....:....|::||||| :|:|:|.
Yeast    10 VDEEYDLWKSNVPLMYDFVSETRLTWPSLTVQWLPTPVQELDGGFIKQELIIGTHTSGEEENYLK 74

Human   124 VARVHIP-----NDDAQFDASHCDSDKGEF-GGFGSVTGKIECEIKINHEGEVNRARYMPQNPHI 182
            .|.:::|     |:|.|.:|..      |: ....:....|....|..||.|:.|||||||:|:|
Yeast    75 FAEINLPKEILSNEDPQEEAGE------EYQSSLPAPRSNIRITAKYEHEEEITRARYMPQDPNI 133

Human   183 IATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCL 247
            :||......|.::..::           .....|:.|:..||.||:::.:.|.|||.||||||.|
Yeast   134 VATINGQGTVFLYSRSE-----------GLQSTLKFHKDNGYALSFSTLVKGRLLSGSDDHTVAL 187

Human   248 WDINAGPKEGKIV----DAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKP 308
            |::.:|....|.|    |.      ||.::.|..||..::.|||:|::|..|.|.|.|:|.|:
Yeast   188 WEVGSGGDPTKPVRTWNDL------HSDIINDNKWHNFNKDLFGTVSEDSLLKINDVRANNTT-- 244

Human   309 SHLVDAHTAEVNC------LSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVC 367
               :|.    |.|      |:|:.:|..:||....|..|.|:||||:|..||....|:|.:
Yeast   245 ---IDT----VKCPQPFNTLAFSHHSSNLLAAAGMDSYVYLYDLRNMKEPLHHMSGHEDAV---- 298

Human   368 DSFLVSVCQEMKSRDSSVKLYQTRGSTIEKNVLYVVLHGDAHRVHWSPHNETILASSGTDRRLNV 432
                                                     :.:.:|.|.:.::.|||:|.||.:
Yeast   299 -----------------------------------------NNLEFSTHVDGVVVSSGSDNRLMM 322

Human   433 WDLSKIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENI 496
            |||.:||.||:.:|||||.|||:.:|.||.:.::||..||..||::.|..|:||:|:|:.:.::
Yeast   323 WDLKQIGAEQTPDDAEDGVPELIMVHAGHRSSVNDFDLNPQIPWLVASAEEENILQVWKCSHSL 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBBP7	XP_047298247.1	CAF1C_H4-bd	62..131	CDD:463513	32/74 (43%)
		WD40	166..491	CDD:475233	110/334 (33%)
		WD40 repeat	171..218	CDD:293791	13/46 (28%)
		WD40 repeat	223..267	CDD:293791	20/47 (43%)
		WD40 repeat	274..308	CDD:293791	14/33 (42%)
		WD40 repeat	319..357	CDD:293791	17/43 (40%)
		WD40 repeat	371..459	CDD:293791	23/87 (26%)
		WD40 repeat	465..490	CDD:293791	11/24 (46%)
HAT2	NP_010858.3	CAF1C_H4-bd	12..82	CDD:463513	31/69 (45%)
		WD40	<117..380	CDD:441893	110/333 (33%)
		WD40 repeat	122..158	CDD:293791	13/46 (28%)
		WD40 repeat	163..204	CDD:293791	19/40 (48%)
		WD40 repeat	212..247	CDD:293791	14/39 (36%)
		WD40 repeat	254..292	CDD:293791	15/37 (41%)
		WD40 repeat	298..349	CDD:293791	23/95 (24%)
		WD40 repeat	355..380	CDD:293791	11/24 (46%)