Protein Alignment RBBP7 and Caf1-55

DIOPT Version :10

• Sequence 1: XP_047298247.1
• Gene: RBBP7 / 5931
• HGNCID: 9890
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_524354.1
• Gene: Caf1-55 / 41836
• FlyBaseID: FBgn0263979
• Length: 430
• Species: Drosophila melanogaster
• Alignment Length: 460
• Identity: 359/460 - (78%)
• Similarity: 391/460 - (85%)
• Gaps: 45/460 - (9%)

Human    51 FEDTVEERVINEEYKIWKKNTPFLYDLVMTHALQWPSLTVQWLPEVTKPEGKDYALHWLVLGTHT 115
            |:|.|||||||||||||||||||||||||||||:|||||.||||:|||.:||||::|.|:|||||
  Fly    12 FDDAVEERVINEEYKIWKKNTPFLYDLVMTHALEWPSLTAQWLPDVTKQDGKDYSVHRLILGTHT 76

Human   116 SDEQNHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIKINHEGEVNRARYMPQNP 180
            |||||||::|.|.:|::|||||.||.|::||||||||||.||||.|||||||||||||||||||.
  Fly    77 SDEQNHLLIASVQLPSEDAQFDGSHYDNEKGEFGGFGSVCGKIEIEIKINHEGEVNRARYMPQNA 141

Human   181 HIIATKTPSSDVLVFDYTKHPAKPDPSGECNPDLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTV 245
            .:|||||||||||||||||||:||:|||||.||||||||||||||||||.||:|:|||||||||:
  Fly   142 CVIATKTPSSDVLVFDYTKHPSKPEPSGECQPDLRLRGHQKEGYGLSWNPNLNGYLLSASDDHTI 206

Human   246 CLWDINAGPKEGKIVDAKAIFTGHSAVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSH 310
            |||||||.|||.:::|||.|||||:|||||||||||||||||||||||||||||||:|.||||||
  Fly   207 CLWDINATPKEHRVIDAKNIFTGHTAVVEDVAWHLLHESLFGSVADDQKLMIWDTRNNNTSKPSH 271

Human   311 LVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHTFESHKDEIFQVCDSFLVSVC 375
            .|||||||||||||||||||||||||||||||||||||||||||:||||||||||
  Fly   272 TVDAHTAEVNCLSFNPYSEFILATGSADKTVALWDLRNLKLKLHSFESHKDEIFQ---------- 326

Human   376 QEMKSRDSSVKLYQTRGSTIEKNVLYVVLHGDAHRVHWSPHNETILASSGTDRRLNVWDLSKIGE 440
                                               |.||||||||||||||||||:|||||||||
  Fly   327 -----------------------------------VQWSPHNETILASSGTDRRLHVWDLSKIGE 356

Human   441 EQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQMAENIYNDEESDVT 505
            |||.||||||||||||||||||||||||||||||||:|||||||||||:||||||:|||||.::.
  Fly   357 EQSTEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWIICSVSEDNIMQVWQMAENVYNDEEPEIP 421

Human   506 TSELE 510
            .||||
  Fly   422 ASELE 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBBP7	XP_047298247.1	CAF1C_H4-bd	62..131	CDD:463513	54/68 (79%)
		WD40	166..491	CDD:475233	253/324 (78%)
		WD40 repeat	171..218	CDD:293791	40/46 (87%)
		WD40 repeat	223..267	CDD:293791	33/43 (77%)
		WD40 repeat	274..308	CDD:293791	31/33 (94%)
		WD40 repeat	319..357	CDD:293791	36/37 (97%)
		WD40 repeat	371..459	CDD:293791	44/87 (51%)
		WD40 repeat	465..490	CDD:293791	23/24 (96%)
Caf1-55	NP_524354.1	CAF1C_H4-bd	23..92	CDD:463513	54/68 (79%)
		WD40 repeat	132..179	CDD:293791	40/46 (87%)
		WD40	<176..409	CDD:441893	212/277 (77%)
		WD40 repeat	184..228	CDD:293791	33/43 (77%)
		WD40 repeat	235..274	CDD:293791	35/38 (92%)
		WD40 repeat	280..318	CDD:293791	36/37 (97%)
		WD40 repeat	324..375	CDD:293791	47/95 (49%)
		WD40 repeat	381..406	CDD:293791	23/24 (96%)