DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tgs1 and tgs1

DIOPT Version :9

Sequence 1:	NP_732316.2	Gene:	Tgs1 / 59260	FlyBaseID:	FBgn0266195	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_003197913.2	Gene:	tgs1 / 100537552	ZFINID:	ZDB-GENE-070802-2	Length:	800	Species:	Danio rerio

Alignment Length:	353	Identity:	144/353 - (40%)
Similarity:	212/353 - (60%)	Gaps:	33/353 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   120 NSEDVEEDLQNLSLTNKPIKSKQQRVTEKEEDESYLTANDDPEDCD---------EEQQLRLLGL 175
            :||||.......:|.....|::...:..::|||...:.:.|.|||:         ||||..:..|
Zfish   468 DSEDVATTSMPEALIGPFDKAELASLPTRKEDEEEASNDTDEEDCETTPQPSRICEEQQHIIPDL 532

  Fly   176 PTSFASKADIINYRKERKTQYELSSSDSEDDHDLLTMENNENEALHGVQSGSVKKKKRRQRQIKK 240
            ......:||         .:.||...|..   |.|..:.:|:.....||  :.||.||::|:.:|
Zfish   533 EEIHEDEAD---------PRGELQPLDVP---DFLLPDAHEDTKKESVQ--AFKKNKRKKRKRRK 583

  Fly   241 LKARMPECMQEDNNKMVKYWVKRFSLFSRFDQGIRLDRESWFSVTPEKIAKQTARRLA-C---DV 301
            .....||...|.  ::.|||.:|:.||||||:||:||.|.||||||||||:..|.|:. |   ::
Zfish   584 DVEMPPEIAAEP--ELAKYWAQRYRLFSRFDEGIKLDHEGWFSVTPEKIAEHIALRVQDCFNTEL 646

  Fly   302 IVDAFCGCGGNAIQFANTCGRVIAVDIDAEKLAMAKHNAGIYGVAHKIEFIHADFLQFAASTKLR 366
            |:|||||.||||||||.|..|||.:|||..:||:|:|||.:|||..:|:|:..||||.|  ..||
Zfish   647 IIDAFCGVGGNAIQFALTGKRVIGIDIDPVRLALAQHNAAVYGVEQRIDFLQGDFLQLA--PHLR 709

  Fly   367 PNVVFLSPPWGGPDYQKQATFDIETGLLPVGASQLMQLSRSLASDVAFFLPRNANMKQVVALSGV 431
            .::||||||||||:|.....|:|:|.:.|.| .::.:||:.::.::.:||||||:|:|:.:|:|.
Zfish   710 GDMVFLSPPWGGPEYLTADVFNIQTMMTPDG-FEIFRLSKMISDNIVYFLPRNADMEQIASLAGP 773

  Fly   432 GQQCEVEHNYLDTRMVALTAYYGKGIIK 459
            |.:.|||.|:|:.::..:|||:| .:||
Zfish   774 GGKVEVEQNFLNNKLKTITAYFG-NLIK 800

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tgs1	NP_732316.2	Methyltransf_15	299..455	CDD:286524	77/158 (49%)
tgs1	XP_003197913.2	Methyltransf_15	645..796	CDD:286524	76/153 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582430
Domainoid	1	1.000	165	1.000	Domainoid score	I3880
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002744
OrthoInspector	1	1.000	-	-		oto40939
orthoMCL	1	0.900	-	-		OOG6_102135
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1507
SonicParanoid	1	1.000	-	-		X2121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.770