Protein Alignment Zwilch and Zwilch

DIOPT Version :10

• Sequence 1: NP_733421.1
• Gene: Zwilch / 59247
• FlyBaseID: FBgn0061476
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: XP_314811.5
• Gene: Zwilch / 1275555
• VectorBaseID: AGAMI1_008876
• Length: 635
• Species: Anopheles gambiae
• Alignment Length: 667
• Identity: 198/667 - (29%)
• Similarity: 327/667 - (49%)
• Gaps: 64/667 - (9%)

  Fly     5 ANLANVYAELMRRCGESYTITYGAPPTYLVSMVGAAEAGKKIVLVFKEDRNGAV-ARLRTTPTRA 68
            ::||||| :|.|...|.....|..||:|:.|:   .|...||:..|::.:|..: :.:.....:.
Mosquito     2 SDLANVY-QLFRSKFEDNDFQYYYPPSYIRSL---TECDDKIIFAFRKVQNHILSSEMDAVRPKQ 62

  Fly    69 APKKEGSADLDLTGSPLKDDCLVDAIADLSIDLQLDHS---NPWKLEEEYQRGIPVDKARSIVCS 130
            :|...|||.||||||||: |...:...::::..:...|   |.|.::||....:..:||||:: .
Mosquito    63 SPNSNGSASLDLTGSPLR-DVSFEQFEEMNLSKEYHESSVQNLWTIDEETYAPLSTEKARSLL-Q 125

  Fly   131 EFLQL--AEGLGSVWFLCDGSDLGQTQLLQYEFNPT-----HFSRGILSYQGVRPAYLVTSQALV 188
            .|:.|  ..|.||:|.||.|:|..|..|||...|..     ||:||::.:.||:|:..:|...|:
Mosquito   126 AFISLECRIGRGSIWVLCCGTDSEQKVLLQLSVNAASNNQRHFTRGVVRFSGVQPSNSITLGQLI 190

  Fly   189 RHHGKTPDETL-------IENSYQVNPHMRLRCSWTSSAALPLLVNLNDCDVALNHTFRVGDCGP 246
            ..|.:...|.:       |:...:::..:.||.||.:...........:..|.|:..|.|.: |.
Mosquito   191 DIHRQRAGEGMKFSPKIQIQQWCKLHAQITLRLSWNAMGEGSTFAIERNARVRLSQEFPVNN-GA 254

  Fly   247 LTQD-----FMNQLRILVYIREDIVSYHTDVKQGVSRDPTYRCGSG-IDMDELRESINQTMTDVS 305
            .::.     |..||:.|..:||.|:....:.:.|.:|:..  ||.. :|::.:::.:|..:   |
Mosquito   255 FSRSSPAEYFWQQLQRLAMMRERIMDIRANRESGYARNDV--CGEAEMDLEYIKQKVNNIL---S 314

  Fly   306 GLIGRYSISNAEFDIEDVVQRAKVRQLTDLTDKLWELLKCCHSYKDLKIAFSMLFQCAARCNIVN 370
            ..:....::.....|.|:|...:.|:|||:.::|::.|..|.||:|||.|...:|..:...||||
Mosquito   315 SFLEVEPVTYNSSTIIDMVSLVQKRKLTDVMERLYDALTLCSSYEDLKAAIDYIFHLSTHSNIVN 379

  Fly   371 TPTNKNRLAKIITELANRRLAMPCLSGAEPLELLLEIGLEKLYKDYEFIYTESKMCSTNLLKDDS 435
            .|||..|.:::|..:...|||:|.|:|:||.|||||.|..||..||..|:||:.:......|
Mosquito   380 VPTNGTRFSQLILAMIQDRLAIPLLTGSEPYELLLECGFSKLMNDYRTIFTEAGIYELEFEK--- 441

  Fly   436 SGASMDDGSPQNLPQLRKSLHNAVRGDPTPGAGMRKTLLHHHGAVNSRST----KYAGSDDDAGF 496
                  ...|| :...|||.:         ..|....|..||||.:.||.    :.|..|:....
Mosquito   442 ------LFQPQ-VTNTRKSRY---------ATGNGPQLDAHHGAPSKRSATQLFQSAAGDERVRE 490

  Fly   497 KN---SHFDEHESTERISKLFQIHCTLEHLLMMHIHLNLANVYNDVCSELLKKPPKLVESIDDQL 558
            |:   |:|||.|...|:::|.|:|..|||||::...:|:.::|..||...|.:.|.....:.::.
Mosquito   491 KSILLSNFDEDEVKLRLNRLAQVHLLLEHLLLLESAVNVPSIYGRVCELYLGRAPYSYGEVYNRR 555

  Fly   559 SDVMDIRLSAHYVRDHLDGKDPYSRHITMRSHNKFRELKTTFYFNSENICPPNLAQCFQCDDKEM 623
            :|:::..|....:....|...|.:|.:||.|.|..::|:|.||.|.:.|.|......|:|  ||:
Mosquito   556 TDLLEFELDEFMLLRKADHVLPCARRVTMSSANMLQKLETVFYQNVKPILPGRFYPQFEC--KEL 618

  Fly   624 VKERTYHSWIYHKIRSL 640
            ..:..:..:.|.:|.||
Mosquito   619 DSKHEFWCYEYDRIESL 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Zwilch	NP_733421.1	Zwilch	29..627	CDD:401684	185/628 (29%)
Zwilch	XP_314811.5	None