DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18530 and lipa

DIOPT Version :9

Sequence 1:	NP_652714.2	Gene:	CG18530 / 59241	FlyBaseID:	FBgn0042207	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001015847.2	Gene:	lipa / 548564	XenbaseID:	XB-GENE-952977	Length:	409	Species:	Xenopus tropicalis

Alignment Length:	376	Identity:	117/376 - (31%)
Similarity:	186/376 - (49%)	Gaps:	35/376 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AEIIASHNYPVEIHTVVTRDGYLLNAFRIPNSIYCEQSGTKPAVLFQHGMTASSDVFLVNGPRDA 86
            :|:|....||.|.:.|:|.|||:|:..|||:.:.....|.||.|..|||:.|....::.|...::
Frog    50 SELIRYRGYPSEEYEVLTEDGYILSVNRIPHGVKYASEGPKPVVFLQHGLLADGSNWVTNLENNS 114

  Fly    87 LPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFWRFSWHEIGTEDVAAFIDYILGTTNQSAV 151
            |.|:||||.:|||:.||||..:||:|.||.|..|:||.||:.|:..:|:.|.:|:|...|.|..:
Frog   115 LGFILADAGYDVWIGNSRGNTWSRKHKSLSPDQEEFWAFSYDELAKKDLPAVVDFITKKTGQEQI 179

  Fly   152 HYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGP-----------------PVFMGHTHTLGQIF 199
            .|||||||.|...:..|..|:..:.:|....|.|                 |.|:     :.::|
Frog   180 FYVGHSQGTTIAFIAFSSLPQLAKKIKMYFGLAPVATVKFSKSPLAKLGVLPEFL-----IEELF 239

  Fly   200 LRTLIMSMPDCEFMFHNRILNKILRRICGLFVVRVYCSTFFMIVNGKFSDHLNTSAIPLIAATLP 264
            .:.        ||:....::..:....|...:....|...|.:::|....:||.|.:.:.::..|
Frog   240 GKG--------EFLPQTYLITWLATHFCTHAIADELCGNIFFLLSGFNEKNLNMSRVNVYSSHCP 296

  Fly   265 AGVSSRQPKHFIQLTDSGRFRPFDFGILRNLINYRSLTPPDYPLHNVRPLT-PVHIFYSDDDLSA 328
            ||.|.:...|:.|...||..:.||||...|:|:|...|||.|   :||.:| |..::...:|..|
Frog   297 AGTSVQNMLHWRQGVRSGELKAFDFGTKGNMIHYNQTTPPFY---HVRDMTVPTALWTGGNDWLA 358

  Fly   329 AKEDVENFATSLPEAVMHRISTPSWHHMDFVHSMTVANVINKPVIEIFKRF 379
            .::||....|.:...|.|: ..|.|.|:||:..:.....:...:|.:.|:|
Frog   359 DRKDVALLLTQVSNLVYHK-EIPDWEHLDFIWGLDAPERMYNEIIAMMKKF 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18530	NP_652714.2	PLN02872	22..377	CDD:215470	115/372 (31%)
CG18530	NP_652714.2	Abhydro_lipase	22..82	CDD:282003	22/59 (37%)
lipa	NP_001015847.2	Abhydro_lipase	49..110	CDD:282003	22/59 (37%)
		PLN02872	50..409	CDD:215470	117/376 (31%)
		Abhydrolase_5	91..>229	CDD:289465	51/137 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.030