DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18530 and CG11608

DIOPT Version :9

Sequence 1:	NP_652714.2	Gene:	CG18530 / 59241	FlyBaseID:	FBgn0042207	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_650218.3	Gene:	CG11608 / 41556	FlyBaseID:	FBgn0038069	Length:	430	Species:	Drosophila melanogaster

Alignment Length:	368	Identity:	195/368 - (52%)
Similarity:	267/368 - (72%)	Gaps:	0/368 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ITSAEIIASHNYPVEIHTVVTRDGYLLNAFRIPNSIYCEQSGTKPAVLFQHGMTASSDVFLVNGP 83
            ||:.:||:||||||:.|||||||||:|:.||||:|..|..|..||.||..||||.|:|.:|:.||
  Fly    46 ITAVDIISSHNYPVQTHTVVTRDGYILSVFRIPSSQLCASSEPKPVVLINHGMTGSADSWLLTGP 110

  Fly    84 RDALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFWRFSWHEIGTEDVAAFIDYILGTTNQ 148
            |:.|||:|||||:||||.|.|||||||:|:.|......||||||||||.||:.|.:|:||.:|.:
  Fly   111 RNGLPFLLADACYDVWLINCRGTRYSRKHLKLKAWLLQFWRFSWHEIGMEDLPATVDHILASTKR 175

  Fly   149 SAVHYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGPPVFMGHTHTLGQIFLRTLIMSMPDCEFM 213
            :::||||||||||:::|:||||||||:.::|.|||.||||:.|:.::|...::.|...:||.|.:
  Fly   176 NSLHYVGHSQGCTSMLVMLSMRPEYNKRIRTTILLAPPVFLKHSLSMGHKIMKPLFNLLPDIELL 240

  Fly   214 FHNRILNKILRRICGLFVVRVYCSTFFMIVNGKFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQL 278
            .|:::||..:..||.:..|:..|:..:::.||:.|.|:|.:.||::.||.|||:|||||:||.||
  Fly   241 PHHKMLNSAVSAICKILGVKDVCTALYLLTNGRVSQHMNRTLIPMLIATHPAGISSRQPRHFFQL 305

  Fly   279 TDSGRFRPFDFGILRNLINYRSLTPPDYPLHNVRPLTPVHIFYSDDDLSAAKEDVENFATSLPEA 343
            .||||||.:|||...|.:.||..|||:|||..|||.:.:||||||||.:.:..||...|:.||.|
  Fly   306 KDSGRFRQYDFGFGMNYLIYRQNTPPEYPLEMVRPHSAIHIFYSDDDGTISPRDVLTLASKLPYA 370

  Fly   344 VMHRISTPSWHHMDFVHSMTVANVINKPVIEIFKRFEQPIDCK 386
            |.|.|:..:|:||||:.:..:..:||.|||:|.|.||:.|..|
  Fly   371 VPHHITDETWNHMDFLLANNINELINNPVIKIIKTFEENIKHK 413

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18530	NP_652714.2	PLN02872	22..377	CDD:215470	188/354 (53%)
CG18530	NP_652714.2	Abhydro_lipase	22..82	CDD:282003	36/59 (61%)
CG11608	NP_650218.3	PLN02872	39..405	CDD:215470	190/358 (53%)
		Abhydro_lipase	49..109	CDD:282003	36/59 (61%)
		Abhydrolase_5	91..>212	CDD:289465	74/120 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439426
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	1	1.000	-	-		H112935
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.900