Protein Alignment CG18530 and LIPA

DIOPT Version :10

• Sequence 1: NP_652714.2
• Gene: CG18530 / 59241
• FlyBaseID: FBgn0042207
• Length: 389
• Species: Drosophila melanogaster
• Sequence 2: NP_001427765.1
• Gene: LIPA / 3988
• HGNCID: 6617
• Length: 443
• Species: Homo sapiens
• Alignment Length: 374
• Identity: 116/374 - (31%)
• Similarity: 178/374 - (47%)
• Gaps: 27/374 - (7%)

  Fly    22 AEIIASHNYPVEIHTVVTRDGYLLNAFRIPNS-IYCEQSGTKPAVLFQHGMTASSDVFLVNGPRD 85
            :|||:...:|.|.:.|.|.|||:|...|||:. ......|.||.|..|||:.|.|..::.|....
Human    82 SEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNHSDKGPKPVVFLQHGLLADSSNWVTNLANS 146

  Fly    86 ALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFWRFSWHEIGTEDVAAFIDYILGTTNQSA 150
            :|.|:||||.||||:.||||..:||:|.:|..|.::||.||:.|:...|:.|.|::||..|.|..
Human   147 SLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEFWAFSYDEMAKYDLPASINFILNKTGQEQ 211

  Fly   151 VHYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGPPVFMGH------------THTLGQIFLRTL 203
            |:|||||||.|...:..|..||..:.:|....|||...:..            .|.:..:|
Human   212 VYYVGHSQGTTIGFIAFSQIPELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIKDLF---- 272

  Fly   204 IMSMPDCEFMFHNRILNKILRRICGLFVVRVYCSTFFMIVNGKFSDHLNTSAIPLIAATLPAGVS 268
                .|.||:..:..|..:...:|...:::..|.....::.|....:||.|.:.:.....|||.|
Human   273 ----GDKEFLPQSAFLKWLGTHVCTHVILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTS 333

  Fly   269 SRQPKHFIQLTDSGRFRPFDFG-ILRNLINYRSLTPPDYPLHNVRP-LTPVHIFYSDDDLSAAKE 331
            .:...|:.|.....:|:.||:| ..:|..:|....||.|   ||:. |.|..::....|..|...
Human   334 VQNMLHWSQAVKFQKFQAFDWGSSAKNYFHYNQSYPPTY---NVKDMLVPTAVWSGGHDWLADVY 395

  Fly   332 DVENFATSLPEAVMHRISTPSWHHMDFVHSMTVANVINKPVIEIFKRFE 380
            ||....|.:...|.|. |.|.|.|:||:..:.....:...:|.:.::::
Human   396 DVNILLTQITNLVFHE-SIPEWEHLDFIWGLDAPWRLYNKIINLMRKYQ 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18530	NP_652714.2	PLN02872	22..377	CDD:215470	116/369 (31%)
LIPA	NP_001427765.1	None