DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18530 and CG7329

DIOPT Version :9

Sequence 1:	NP_652714.2	Gene:	CG18530 / 59241	FlyBaseID:	FBgn0042207	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001260357.1	Gene:	CG7329 / 34457	FlyBaseID:	FBgn0032271	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	404	Identity:	128/404 - (31%)
Similarity:	195/404 - (48%)	Gaps:	38/404 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPYK--TLVILSVCTQIVNGI-------------------TSAEIIASHNYPVEIHTVVTRDGYL 44
            ||:.  .||:|.:.|...:|:                   .:.:::..:.:|.|.|.|.|.|.|:
  Fly     1 MPHAICILVVLGIYTLDGSGVLGGFMENTYPASVIEDAHLNTIQLLEKYKHPAETHQVTTDDKYI 65

  Fly    45 LNAFRIPNSIYCEQSGTKPAVLFQHGMTASSDVFLVNGPRDALPFMLADACFDVWLSNSRGTRYS 109
            |...||      .:.|.|| ||..||:..:|..::|.||...|.:.|....:|||:.|.||.|||
  Fly    66 LTLHRI------ARPGAKP-VLLVHGLEDTSSTWIVMGPESGLGYFLYANGYDVWMGNVRGNRYS 123

  Fly   110 RRHVSLDP-SDEDFWRFSWHEIGTEDVAAFIDYILGTTNQSAVHYVGHSQGCTTLVVLLSMRPEY 173
            :.||.|:| :|:.:|.|||||||..|:.|.||.:|..|....:.|.|||||.|:..|:.|.||||
  Fly   124 KGHVKLNPNTDKSYWSFSWHEIGMYDLPAMIDGVLQKTGYQKLSYFGHSQGTTSFFVMASSRPEY 188

  Fly   174 NQFVKTAILLGPPVFMGHTHT-LGQIFLRTLIMSMPDCEFMFHNRI-LNKILRRICGLFVVRVYC 236
            |..:.....|.|..||.|... |..|....:.|...:.|...|:.: ||:.|.....|..    |
  Fly   189 NAKIHLMSALAPVAFMKHMKAPLMGIARMGMNMFGDNFELFPHSEVFLNQCLSSAAMLKT----C 249

  Fly   237 STFFMIVNGKFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQLTDSGRFRPFDFGILRNLINYRSL 301
            ..|:..:.||..:..|.:..|::...||.|.:.:|..|::|:..|.||..:|:....|...|...
  Fly   250 MRFYWQIVGKNREEQNMTMFPVVLGHLPGGCNIKQALHYLQMQKSDRFCQYDYESKENQRLYGRS 314

  Fly   302 TPPDYPLHNVRPLTPVHIFYSDDDLSAAKEDVENFATSLPEAVMHRISTPSWHHMDFVHSMTVAN 366
            |||||.|..::  .||.::|..:|..:|.|||...|..||..|.:.:.. .|:|||.:..::...
  Fly   315 TPPDYRLERIK--APVALYYGSNDYLSAVEDVHRLAKVLPNVVENHLYR-KWNHMDMIWGISARR 376

  Fly   367 VINKPVIEIFKRFE 380
            .|...::::.:.:|
  Fly   377 SIQPRILQVMQYWE 390

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18530	NP_652714.2	PLN02872	22..377	CDD:215470	120/357 (34%)
CG18530	NP_652714.2	Abhydro_lipase	22..82	CDD:282003	19/59 (32%)
CG7329	NP_001260357.1	Abhydro_lipase	42..96	CDD:282003	19/60 (32%)
		Abhydrolase	73..239	CDD:304388	67/166 (40%)
		Abhydrolase_1	77..371	CDD:278959	108/301 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439535
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900