DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18530 and CG2772

DIOPT Version :9

Sequence 1:	NP_652714.2	Gene:	CG18530 / 59241	FlyBaseID:	FBgn0042207	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_608776.1	Gene:	CG2772 / 33559	FlyBaseID:	FBgn0031533	Length:	416	Species:	Drosophila melanogaster

Alignment Length:	403	Identity:	161/403 - (39%)
Similarity:	224/403 - (55%)	Gaps:	44/403 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPYKTLVILSVCTQIVNGITSAEIIASHNYPVEIHTVVTRDGYLLNAFRIPNSIYCEQSG----- 60
            :|:|.|.            ||||.||.|.||.|.|.|.|.|||:||.||||:|.....:|
  Fly    27 IPFKRLK------------TSAERIAEHGYPAESHFVETPDGYVLNVFRIPHSPKLNSNGNEGES 79

  Fly    61 --TKPAVLFQHGMTASSDVFLVNGPRDALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFW 123
              ::|.||..||:.:.||.||:|||.||||:..|||.:||||.|:||..|||.:..|:.....||
  Fly    80 EASRPVVLIMHGLFSCSDCFLLNGPEDALPYNYADAGYDVWLGNARGNIYSRNNTRLNVKHPYFW 144

  Fly   124 RFSWHEIGTEDVAAFIDYILGTTNQSAVHYVGHSQGCTTLVVLLSMRPEYNQFVKTAILLGPPVF 188
            :|||||||:.|:.|.|||||..|.|.::||||||||||:..|:.|.|||||..:|||.:|.|||:
  Fly   145 KFSWHEIGSIDLPATIDYILAETGQQSLHYVGHSQGCTSFFVMGSYRPEYNAKIKTAHMLAPPVY 209

  Fly   189 MGHT--------------HTLGQIFLRTLIMSMPDCEFMFHNRILNKILRRICGLFVVRV-YCST 238
            ||::              |.:|...|...:: :|      .|..:.::|...|....:.: ||.|
  Fly   210 MGNSTEGLIVSTAPLFGHHGIGSTLLENQVL-LP------QNAFIQRVLDTTCSNQPIMLSYCKT 267

  Fly   239 FFMIVNGKFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQLTDSGRFRPFDFGILRNLINYRSLTP 303
            ..::..|....:||.:.:|.||.|.||||||.|..|:||...|..||.:|:|..|||..|....|
  Fly   268 LAILWGGPEIGNLNQTLLPQIAETHPAGVSSNQAIHYIQSYASNDFRLYDWGSKRNLEYYGVSEP 332

  Fly   304 PDYPLHNVRPLTPVHIFYSDDDLSAAKEDVENFATSLPE-AVMHRISTPSWHHMDFVHSMTVANV 367
            |.|.|..:  .:.::::|...|.||.|:|:......||. |::|.:...:|.|:||:.:..|..|
  Fly   333 PAYDLTKI--TSELYLYYGLADGSANKQDISRLPDLLPNLALLHEVPDSTWGHLDFIFATEVKRV 395

  Fly   368 INKPVIEIFKRFE 380
            ||..|::..|.::
  Fly   396 INDLVLDYSKAYD 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18530	NP_652714.2	PLN02872	22..377	CDD:215470	155/377 (41%)
CG18530	NP_652714.2	Abhydro_lipase	22..82	CDD:282003	31/66 (47%)
CG2772	NP_608776.1	PLN02872	5..393	CDD:215470	155/386 (40%)
		Abhydro_lipase	36..103	CDD:282003	31/66 (47%)
		Abhydrolase	113..>196	CDD:304388	48/82 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471650
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	1	1.000	-	-		H112935
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	11	10.900