DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18530 and lipl-8

DIOPT Version :9

Sequence 1:	NP_652714.2	Gene:	CG18530 / 59241	FlyBaseID:	FBgn0042207	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_506641.1	Gene:	lipl-8 / 190108	WormBaseID:	WBGene00013050	Length:	401	Species:	Caenorhabditis elegans

Alignment Length:	398	Identity:	113/398 - (28%)
Similarity:	180/398 - (45%)	Gaps:	33/398 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VILSVCTQIVNGITSAEIIASHNYPVEIHTVVTRDGYLLNAFRIP------NSIYCEQSGTKPAV 65
            ::.:...:|...:.:|:.|:.:.|.||.|.|.|.|||.:...|||      :.:.|.:   :|.|
Worm    11 IVFAFGKEIEETLDAADTISHYGYTVEKHYVTTDDGYTVQLQRIPVGRDDRSILGCSK---RPVV 72

  Fly    66 LFQHGMTASSDVFLVNGPRDALPFMLADACFDVWLSNSRGTRYSRRHVSLDPSDEDFWRFSWHEI 130
            .|.||:..||..||:|.|..:..::.|||.|||||.|.|||.|...|.|...:..:||.||.:|.
Worm    73 FFMHGLFGSSYHFLLNLPSQSAAYIFADAGFDVWLGNIRGTEYGLNHTSFSTNGVNFWNFSLYEH 137

  Fly   131 GTEDVAAFIDYILGTTNQSAVHYVGHSQGCTTLVVLLSMRP-EYNQFVKTAILLGPPV-----FM 189
            ...|:...|:|:|..|...::.|||||||...:...|:... .:...::....|||..     .|
Worm   138 SHYDLRQQIEYVLDYTRHESLFYVGHSQGTAVMFARLAEADVTWQSKIRVFFALGPTAGFMKPLM 202

  Fly   190 GHTHTLGQIFLRTLIMSMPDCEFMFHNRILN-KILRRICGLFV-------VRVYCSTFFMIVNG- 245
            ..| .|.:.:|:.||....|.:|    .||. :|.|.|...|.       ....||..|.:..|
Worm   203 PFT-LLEENYLQALIQFALDGKF----GILPVEIPRAIASKFADFCSSKFFTFLCSAGFKVAAGI 262

  Fly   246 KFSDHLNTSAIPLIAATLPAGVSSRQPKHFIQLTDSGRFRPFDFGILRNLINYRSLTPPDYPLHN 310
            :....:|.|.||:|.:..|:..|:....|::|:......|..|.|..||||.|.....|...:.|
Worm   263 ETLGQVNDSRIPIILSHFPSATSTLNLLHWMQIFKYHELRRLDLGTARNLIAYGQKDAPRLEIGN 327

  Fly   311 VRPLTPVHIFYSDDDLSAAKEDV-ENFATSLPEAVMHRISTPSWHHMDFVHSMTVANVINKPVI- 373
            :  :....:::|.||....:.|| |.....:...::.......:.|.||:..:...:.:.||::
Worm   328 I--IAQTILYFSKDDQITDEVDVREIIMKQMGPGLIESYDLDHFTHFDFILGLRATDEVYKPIVY 390

  Fly   374 EIFKRFEQ 381
            .|:|..::
Worm   391 RIYKELKK 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18530	NP_652714.2	PLN02872	22..377	CDD:215470	111/377 (29%)
CG18530	NP_652714.2	Abhydro_lipase	22..82	CDD:282003	24/65 (37%)
lipl-8	NP_506641.1	PLN02872	26..401	CDD:215470	112/383 (29%)
		Abhydro_lipase	26..89	CDD:282003	24/65 (37%)
		Abhydrolase_5	71..>193	CDD:289465	44/121 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930