DRSC/TRiP Functional Genomics Resources

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Protein Alignment GstD10 and GDAP1

DIOPT Version :9

Sequence 1:NP_001287302.1 Gene:GstD10 / 59240 FlyBaseID:FBgn0042206 Length:210 Species:Drosophila melanogaster
Sequence 2:NP_061845.2 Gene:GDAP1 / 54332 HGNCID:15968 Length:358 Species:Homo sapiens


Alignment Length:261 Identity:49/261 - (18%)
Similarity:86/261 - (32%) Gaps:77/261 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 LYYRPGSAPCRSV--LMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWE 65
            ||:...|...:.|  ::..|||..|   :..::....|...|.::::|....:|.|......:.|
Human    28 LYHWTHSFSSQKVRLVIAEKALKCE---EHDVSLPLSEHNEPWFMRLNSTGEVPVLIHGENIICE 89

  Fly    66 SRAIMVYLVEKY----------GKDDKLFPK----------------------------DVQKQA 92
            :..|:.||.:.:          .|:...:|:                            |....|
Human    90 ATQIIDYLEQTFLDERTPRLMPDKESMYYPRVQHYRELLDSLPMDAYTHGCILHPELTVDSMIPA 154

  Fly    93 LINQRLYFDMGTL---YKSFSE--------YYYPQIFLK-KPANEENYKKIEVAFEFLNTFL--- 142
            ....|:...:|..   .|..:|        |...|..|| |..:.:|.|.::...:.|...|   
Human   155 YATTRIRSQIGNTESELKKLAEENPDLQEAYIAKQKRLKSKLLDHDNVKYLKKILDELEKVLDQV 219

  Fly   143 -------------EG-QTYSAGGDYSLADIAFLATVSTFDVAGFDFKRYANVAR-----WYENAK 188
                         || |.:..|..::|||::...|:......||..:.:.|..|     :||...
Human   220 ETELQRRNEETPEEGQQPWLCGESFTLADVSLAVTLHRLKFLGFARRNWGNGKRPNLETYYERVL 284

  Fly   189 K 189
            |
Human   285 K 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GstD10NP_001287302.1 GST_N_Delta_Epsilon 1..75 CDD:239343 17/73 (23%)
PLN02473 3..196 CDD:166114 49/261 (19%)
GST_C_Delta_Epsilon 89..205 CDD:198287 29/135 (21%)
GDAP1NP_061845.2 GST_N_GDAP1 26..98 CDD:239350 16/72 (22%)
GST_C_GDAP1 179..289 CDD:198336 24/107 (22%)
Required for mitochondrial localization 320..358
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165154505
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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