DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD10 and GstE6

DIOPT Version :9

Sequence 1:	NP_001287302.1	Gene:	GstD10 / 59240	FlyBaseID:	FBgn0042206	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_611328.1	Gene:	GstE6 / 37111	FlyBaseID:	FBgn0063494	Length:	222	Species:	Drosophila melanogaster

Alignment Length:	216	Identity:	78/216 - (36%)
Similarity:	126/216 - (58%)	Gaps:	14/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDLYYRPGSAPCRSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLHDHGFALWE 65
            :.||....|.|.|:|.:|..||.:.::... ::..||.|.:||||:.|||||:|||.|.|..:|:
  Fly     4 LTLYGLDPSPPVRAVKLTLAALNLTYEYVN-VDIVARAQLSPEYLEKNPQHTVPTLEDDGHYIWD 67

  Fly    66 SRAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDMGTLY----KSFSEYYYPQIFLKKPANEE 126
            |.||:.|||.||...|.|:|||..|:|:::|||:|:.|.::    :|.|:....|...|.|  :|
  Fly    68 SHAIIAYLVSKYADSDALYPKDPLKRAVVDQRLHFESGVVFANGIRSISKSVLFQGQTKVP--KE 130

  Fly   127 NYKKIEVAFEFLNTFLEGQTYSAGGDYSLADIAFLATVSTFDV-AGFDFKRYANVARWYENAKKL 190
            .|..|...::|:.|||:||.|.||...::||.:.:::|::.:. ...|..:|..:..|.:..::|
  Fly   131 RYDAIIEIYDFVETFLKGQDYIAGNQLTIADFSLVSSVASLEAFVALDTTKYPRIGAWIKKLEQL 195

  Fly   191 TPGWEE-NWAGCQE----FRK 206
             |.:|| |..|.::    |:|
  Fly   196 -PYYEEANGKGVRQLVAIFKK 215

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD10	NP_001287302.1	GST_N_Delta_Epsilon	1..75	CDD:239343	32/73 (44%)
		PLN02473	3..196	CDD:166114	72/197 (37%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	36/125 (29%)
GstE6	NP_611328.1	GstA	4..196	CDD:223698	71/195 (36%)
		GST_N_Delta_Epsilon	4..77	CDD:239343	32/73 (44%)
		GST_C_Delta_Epsilon	91..209	CDD:198287	36/120 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460285
Domainoid	1	1.000	54	1.000	Domainoid score	I4138
eggNOG	1	0.900	-	-		E1_COG0625
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	77	1.000	Inparanoid score	I2398
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1231780at2759
OrthoFinder	1	1.000	-	-		FOG0000035
OrthoInspector	1	1.000	-	-		mtm975
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43969
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X30
	10	9.900