DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GstD10 and GSTZ1

DIOPT Version :9

Sequence 1:	NP_001287302.1	Gene:	GstD10 / 59240	FlyBaseID:	FBgn0042206	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_001350632.1	Gene:	GSTZ1 / 2954	HGNCID:	4643	Length:	217	Species:	Homo sapiens

Alignment Length:	189	Identity:	44/189 - (23%)
Similarity:	82/189 - (43%)	Gaps:	23/189 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YYRPGSAPCRSVLMTAKAL-GVEFDKKTI-INTRAREQFTPEYLKINPQHTIPTLHDHGFALWES 66
            |:|   :.|...:..|.|| |::::...| :.....:||:.::..:||...:|||...|..:.:|
Human    12 YFR---SSCSWRVRIALALKGIDYETVPINLIKDGGQQFSKDFQALNPMKQVPTLKIDGITIHQS 73

  Fly    67 RAIMVYLVEKYGKDDKLFPKDVQKQALINQRLYFDM--GTLYKSFSEYYYPQIFLKKPANEE--- 126
            .||:.|| |:.....:|.|:|.:|:|.:  |:..|:  |.:..      ...:.:.|...||
Human    74 LAIIEYL-EEMRPTPRLLPQDPKKRASV--RMISDLIAGGIQP------LQNLSVLKQVGEEMQL 129

  Fly   127 --NYKKIEVAFEFLNTFLEGQT--YSAGGDYSLADIAFLATVSTFDVAGFDFKRYANVA 181
              ....|...|..|...|:...  |..|.:.::||:..:..|:..:....|...|..::
Human   130 TWAQNAITCGFNALEQILQSTAGIYCVGDEVTMADLCLVPQVANAERFKVDLTPYPTIS 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GstD10	NP_001287302.1	GST_N_Delta_Epsilon	1..75	CDD:239343	21/72 (29%)
		PLN02473	3..196	CDD:166114	44/189 (23%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	19/102 (19%)
GSTZ1	NP_001350632.1	maiA	8..212	CDD:273527	44/189 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810