Protein Alignment GstD10 and CLIC1

DIOPT Version :10

• Sequence 1: NP_652713.1
• Gene: GstD10 / 59240
• FlyBaseID: FBgn0042206
• Length: 210
• Species: Drosophila melanogaster
• Sequence 2: NP_001279.2
• Gene: CLIC1 / 1192
• HGNCID: 2062
• Length: 241
• Species: Homo sapiens
• Alignment Length: 228
• Identity: 48/228 - (21%)
• Similarity: 81/228 - (35%)
• Gaps: 63/228 - (27%)

  Fly     1 MDLYYRPGS-----APC---RSVLMTAKALGVEFDKKTIINTRAREQFTPEYLKINPQHTIPTLH 57
            ::|:.:.||     ..|   :.:.|.....||.|: .|.::|:.|   |....|:.|...:|
Human     8 VELFVKAGSDGAKIGNCPFSQRLFMVLWLKGVTFN-VTTVDTKRR---TETVQKLCPGGQLP--- 65

  Fly    58 DHGFALWESRAIMVYLVEKYGKDDK--------LFPKDVQKQALINQRLYFDMGTLYKSFSEYYY 114
                       .::|..|.:...:|        |.|....|.|.:|.........::..||.|
Human    66 -----------FLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAY-- 117

  Fly   115 PQIFLKKPANEENYKK-IEVAFEFLNTFL---------------EG---QTYSAGGDYSLADIAF 160
              |....||..:|.:| :..|.:.|:.:|               ||   :.:..|.:.:|||...
Human   118 --IKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNL 180

  Fly   161 LATVSTFDVA-----GFDF-KRYANVARWYENA 187
            |..:....|.     ||.. :.:..|.|:..||
Human   181 LPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNA 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GstD10	NP_652713.1	GST_N_Delta_Epsilon	1..75	CDD:239343	16/81 (20%)
		GST_C_Delta_Epsilon	89..205	CDD:198287	28/124 (23%)
CLIC1	NP_001279.2	Required for insertion into the membrane	2..90		19/99 (19%)
		O-ClC	6..241	CDD:129941	48/228 (21%)
		G-site. /evidence=ECO:0000305|PubMed:25581026	24..27		1/2 (50%)