DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and ZNF101

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_149981.2	Gene:	ZNF101 / 94039	HGNCID:	12881	Length:	436	Species:	Homo sapiens

Alignment Length:	151	Identity:	52/151 - (34%)
Similarity:	82/151 - (54%)	Gaps:	5/151 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 IERKRLQRKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQG 311
            |....|::..:  |::||::.:..|:...|...|:|.|.:.||:|.|.|.....:..|:| .|.|
Human   273 IRSHALEKSHQ--CQECGKKLSCSSSLHRHERTHSGGKLYECQKCAKVFRCPTSLQAHER-AHTG 334

  Fly   312 EKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTIC 376
            |:||:|..|.|:|:..:....|::||:..|||.|..|.|.|...|..:|||:.|||.:.|.|..|
Human   335 ERPYECNKCGKTFNYPSCFRRHKKTHSGEKPYECTRCGKAFGWCSSLRRHEMTHTGEKPFDCKQC 399

  Fly   377 KQSFQRNTHLKAHLRSKFHTA 397
            .:.|..:.:|:.|.|:  |.|
Human   400 GKVFTFSNYLRLHERT--HLA 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	5/19 (26%)
		zf-H2C2_2	272..297	CDD:290200	9/24 (38%)
		C2H2 Zn finger	288..309	CDD:275368	7/20 (35%)
		C2H2 Zn finger	317..337	CDD:275368	5/19 (26%)
		C2H2 Zn finger	345..365	CDD:275368	8/19 (42%)
		C2H2 Zn finger	373..391	CDD:275368	5/17 (29%)
ZNF101	NP_149981.2	KRAB	4..>46	CDD:214630
		KRAB	4..43	CDD:279668
		C2H2 Zn finger	104..124	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..164
		lambda-1	149..>209	CDD:212564
		C2H2 Zn finger	171..191	CDD:275368
		COG5048	<176..357	CDD:227381	26/86 (30%)
		C2H2 Zn finger	199..219	CDD:275368
		C2H2 Zn finger	227..247	CDD:275368
		zf-H2C2_2	240..264	CDD:290200
		C2H2 Zn finger	255..276	CDD:275368	1/2 (50%)
		C2H2 Zn finger	284..304	CDD:275368	5/19 (26%)
		C2H2 Zn finger	312..332	CDD:275368	7/20 (35%)
		zf-H2C2_2	324..349	CDD:290200	11/25 (44%)
		COG5048	336..>407	CDD:227381	27/70 (39%)
		C2H2 Zn finger	340..360	CDD:275368	5/19 (26%)
		zf-H2C2_2	353..375	CDD:290200	9/21 (43%)
		C2H2 Zn finger	368..388	CDD:275368	8/19 (42%)
		zf-H2C2_2	380..404	CDD:290200	9/23 (39%)
		C2H2 Zn finger	396..416	CDD:275368	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050