DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZNF202

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_001288708.1 Gene:ZNF202 / 7753 HGNCID:12994 Length:648 Species:Homo sapiens


Alignment Length:478 Identity:117/478 - (24%)
Similarity:162/478 - (33%) Gaps:125/478 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    22 HIENE-KMLQDINLVTGTTLHNDPELP-------SSICACCTLDLNQAILFRERCIL-------- 70
            |.|.| :.||:    :...:..||:||       |.:.|..|......:.|::..:.        
Human   193 HQEEELQTLQE----SEVPVPEDPDLPAERSSGDSEMVALLTALSQGLVTFKDVAVCFSQDQWSD 253

  Fly    71 ---TQKQLVHRRRSPEAKEPAEDVEEMASPPDC-----LNDPFGEVDEYIVESPEEVLDHDSDAH 127
               |||               |...|.....||     |:.|....||......||....|....
Human   254 LDPTQK---------------EFYGEYVLEEDCGIVVSLSFPIPRPDEISQVREEEPWVPDIQEP 303

  Fly   128 HDLDEDNYIDSVEDVDALQDMAEVAEEDSQDVESLISSVQKELE-------SICNDDSNSDNNDY 185
            .:..|...:......|..:|..|..|::...:|.:...|..|.|       .|..:|:....|:.
Human   304 QETQEPEILSFTYTGDRSKDEEECLEQEDLSLEDIHRPVLGEPEIHQTPDWEIVFEDNPGRLNER 368

  Fly   186 MEPQNGSYFNETINEYEVSSNPNTPL---PESKSAAGRS-------TKPATTKPKRK-------- 232
            ....|.|..|..:|..|  :.|..||   ....|..|:|       .:...|....|        
Human   369 RFGTNISQVNSFVNLRE--TTPVHPLLGRHHDCSVCGKSFTCNSHLVRHLRTHTGEKPYKCMECG 431

  Fly   233 KQYVTWKNMTEEQII-----------ERKRLQR-------------KRECVCEQCGRQFTDQSNF 273
            |.|....::...|.:           .||.|:.             ::...|:.||:.|...|:.
Human   432 KSYTRSSHLARHQKVHKMNAPYKYPLNRKNLEETSPVTQAERTPSVEKPYRCDDCGKHFRWTSDL 496

  Fly   274 KLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNTRLIHERTHT 338
            ..|...|||.|.|.|..|||.|....::|.||| ||.|.|||.|..|.:.|......|.|.:||.
Human   497 VRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQR-IHLGGKPYLCGECGEDFSEHRRYLAHRKTHA 560

  Fly   339 NAKPYSCHHCDKCF-------------------------KSASGRK---RHELIHTGVRAFACTI 375
            ..:.|.|..|.:||                         ||.|.|.   ||:..|||.:.|.|..
Human   561 AEELYLCSECGRCFTHSAAFAKHLRGHASVRPCRCNECGKSFSRRDHLVRHQRTHTGEKPFTCPT 625

  Fly   376 CKQSFQRNTHLKAHLRSKFHTAK 398
            |.:||.|..||..|.|:  |:.|
Human   626 CGKSFSRGYHLIRHQRT--HSEK 646

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871 16/71 (23%)
C2H2 Zn finger 260..280 CDD:275368 6/19 (32%)
zf-H2C2_2 272..297 CDD:290200 11/24 (46%)
C2H2 Zn finger 288..309 CDD:275368 9/20 (45%)
C2H2 Zn finger 317..337 CDD:275368 5/19 (26%)
C2H2 Zn finger 345..365 CDD:275368 10/47 (21%)
C2H2 Zn finger 373..391 CDD:275368 8/17 (47%)
ZNF202NP_001288708.1 SCAN 43..153 CDD:128708
SCAN 43..130 CDD:280241
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 146..221 9/31 (29%)
KRAB 237..297 CDD:214630 14/74 (19%)
KRAB 237..277 CDD:279668 8/54 (15%)
COG5048 397..>644 CDD:227381 68/249 (27%)
C2H2 Zn finger 399..419 CDD:275368 3/19 (16%)
zf-H2C2_2 411..436 CDD:290200 4/24 (17%)
C2H2 Zn finger 427..447 CDD:275368 3/19 (16%)
C2H2 Zn finger 483..503 CDD:275368 6/19 (32%)
zf-H2C2_2 495..520 CDD:290200 11/24 (46%)
C2H2 Zn finger 511..531 CDD:275368 9/20 (45%)
C2H2 Zn finger 539..559 CDD:275368 5/19 (26%)
C2H2 Zn finger 567..587 CDD:275368 4/19 (21%)
zf-C2H2 593..615 CDD:278523 6/21 (29%)
C2H2 Zn finger 595..615 CDD:275368 6/19 (32%)
zf-H2C2_2 607..632 CDD:290200 10/24 (42%)
C2H2 Zn finger 623..643 CDD:275368 9/21 (43%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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