DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZNF75D

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_009062.2 Gene:ZNF75D / 7626 HGNCID:13145 Length:510 Species:Homo sapiens


Alignment Length:361 Identity:99/361 - (27%)
Similarity:149/361 - (41%) Gaps:82/361 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 QKQL---VHRRRSPEAKEPAEDVE-------------EMASP---PDCLN-DPFGEVDEYIVESP 116
            |:||   .|:...|..:....|.:             :|||.   |:.|: ..|.:|..|..|..
Human   184 QEQLGWNTHKETQPVYERAVHDQQMLALSEQKRIKHWKMASKLILPESLSLLTFEDVAVYFSEEE 248

  Fly   117 EEVLDHDSDAHHDLDEDNYIDSVEDVDALQDMAEVAEEDSQDVESLISSVQKELESICNDDSNSD 181
            .::|       :.|::..|.|.::|:                .|::||...|    :.||..|. 
Human   249 WQLL-------NPLEKTLYNDVMQDI----------------YETVISLGLK----LKNDTGND- 285

  Fly   182 NNDYMEPQNGSYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATT-----------KPKRKKQY 235
                 .|.:.|......:..|||.  .|.:..::...||. .|..|           :.||||..
Human   286 -----HPISVSTSEIQTSGCEVSK--KTRMKIAQKTMGRE-NPGDTHSVQKWHRAFPRKKRKKPA 342

  Fly   236 VTWKNMTEEQIIERKRLQRKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRF----- 295
            ...:.:.:...:..|....::...|::||:.|...|:...|...|||.|.:.||||.:||     
Human   343 TCKQELPKLMDLHGKGPTGEKPFKCQECGKSFRVSSDLIKHHRIHTGEKPYKCQQCDRRFRWSSD 407

  Fly   296 YTDHLMTLHQRIIHQGEKPYDCRFCTKSF-HNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRK 359
            ...|.||      |||.|||.|.:|.||| ||:|.. .|:|.||..||:.|..|.|.|...|...
Human   408 LNKHFMT------HQGIKPYRCSWCGKSFSHNTNLH-THQRIHTGEKPFKCDECGKRFIQNSHLI 465

  Fly   360 RHELIHTGVRAFACTICKQSFQRNTHLKAHLRSKFH 395
            :|:..|||.:.:.|::||::|.|.:.|..|  .|.|
Human   466 KHQRTHTGEQPYTCSLCKRNFSRRSSLLRH--QKLH 499

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871 1/2 (50%)
C2H2 Zn finger 260..280 CDD:275368 6/19 (32%)
zf-H2C2_2 272..297 CDD:290200 11/29 (38%)
C2H2 Zn finger 288..309 CDD:275368 9/25 (36%)
C2H2 Zn finger 317..337 CDD:275368 10/20 (50%)
C2H2 Zn finger 345..365 CDD:275368 6/19 (32%)
C2H2 Zn finger 373..391 CDD:275368 7/17 (41%)
ZNF75DNP_009062.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..35
SCAN 45..133 CDD:307924
KRAB 234..275 CDD:307490 12/63 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 313..343 8/30 (27%)
zf-C2H2 365..387 CDD:306579 6/21 (29%)
C2H2 Zn finger 367..387 CDD:275368 6/19 (32%)
COG5048 <378..>492 CDD:227381 49/120 (41%)
C2H2 Zn finger 395..415 CDD:275368 9/25 (36%)
C2H2 Zn finger 423..443 CDD:275368 10/20 (50%)
C2H2 Zn finger 451..471 CDD:275368 6/19 (32%)
C2H2 Zn finger 479..499 CDD:275368 8/21 (38%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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