DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZNF19

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_008892.2 Gene:ZNF19 / 7567 HGNCID:12981 Length:458 Species:Homo sapiens


Alignment Length:277 Identity:83/277 - (29%)
Similarity:118/277 - (42%) Gaps:60/277 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 AEVAEEDSQDVESLISSVQKELESICNDDSNSDNNDYMEPQNGSYFNETINEYEVSSNPNTPLPE 213
            ||..:...:|||:.|.|....::.|      |:..|.|....                      :
Human    83 AERTKNVCKDVETNIDSESTLIQGI------SEERDGMMSHG----------------------Q 119

  Fly   214 SKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIERKRLQRKRECVCEQCGRQFTDQSNFKLHML 278
            .||...|:..|.|...::.:...|.||:..:  :.|....|| ..:||:||:.|:..|.:..|..
Human   120 LKSVPQRTDFPETRNVEKHQDIPTVKNIQGK--VPRIPCARK-PFICEECGKSFSYFSYYARHQR 181

  Fly   279 RHTGNKNFACQQCGKRFYTDHLMTLHQRI---------------------------IHQGEKPYD 316
            .|||.|.|.|.:|||.|..:..:..||||                           ||.|::||.
Human   182 IHTGEKPFECSECGKAFNGNSSLIRHQRIHTGERPYQCEECGRAFNDNANLIRHQRIHSGDRPYY 246

  Fly   317 CRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQ 381
            |..|..||.:|:..:||:|.||..|||.|:.|.|.|...|...||:.||||.:.:.|..|.:||.
Human   247 CTECGNSFTSSSEFVIHQRIHTGEKPYECNECGKAFVGNSPLLRHQKIHTGEKPYECNECGKSFG 311

  Fly   382 RNTHLKAHLRSKFHTAK 398
            |.:||..|.|  .||.:
Human   312 RTSHLSQHQR--IHTGE 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871
C2H2 Zn finger 260..280 CDD:275368 7/19 (37%)
zf-H2C2_2 272..297 CDD:290200 11/24 (46%)
C2H2 Zn finger 288..309 CDD:275368 9/47 (19%)
C2H2 Zn finger 317..337 CDD:275368 8/19 (42%)
C2H2 Zn finger 345..365 CDD:275368 7/19 (37%)
C2H2 Zn finger 373..391 CDD:275368 8/17 (47%)
ZNF19NP_008892.2 KRAB 14..73 CDD:214630
KRAB 14..53 CDD:279668
COG5048 <96..426 CDD:227381 78/264 (30%)
C2H2 Zn finger 163..183 CDD:275368 7/19 (37%)
zf-H2C2_2 178..199 CDD:290200 10/20 (50%)
C2H2 Zn finger 191..211 CDD:275368 8/19 (42%)
zf-H2C2_2 203..227 CDD:290200 4/23 (17%)
C2H2 Zn finger 219..239 CDD:275368 0/19 (0%)
zf-H2C2_2 231..256 CDD:290200 9/24 (38%)
C2H2 Zn finger 247..267 CDD:275368 8/19 (42%)
zf-H2C2_2 263..283 CDD:290200 10/19 (53%)
C2H2 Zn finger 275..295 CDD:275368 7/19 (37%)
zf-H2C2_2 288..312 CDD:290200 10/23 (43%)
C2H2 Zn finger 303..323 CDD:275368 9/21 (43%)
zf-H2C2_2 315..339 CDD:290200 6/14 (43%)
C2H2 Zn finger 331..351 CDD:275368
zf-H2C2_2 344..367 CDD:290200
C2H2 Zn finger 359..379 CDD:275368
zf-H2C2_2 372..393 CDD:290200
C2H2 Zn finger 387..407 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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