DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and GZF1

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001303941.1	Gene:	GZF1 / 64412	HGNCID:	15808	Length:	711	Species:	Homo sapiens

Alignment Length:	157	Identity:	52/157 - (33%)
Similarity:	72/157 - (45%)	Gaps:	27/157 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 CEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRI----------------- 307
            |.:||.:|:..|..|.||..|||.|.|.|.:||.||..:|::..|:|.
Human   437 CTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFA 501

  Fly   308 ----------IHQGEKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHE 362
                      ||.|.||:.|..|.::|...|:...|.:.||..:||.|..|.|.|...:..:||.
Human   502 SKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHR 566

  Fly   363 LIHTGVRAFACTICKQSFQRNTHLKAH 389
            .||||.|.|.|..|.::|...:.|:.|
Human   567 RIHTGERPFMCNACGRTFTDKSTLRRH 593

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	8/19 (42%)
		zf-H2C2_2	272..297	CDD:290200	13/24 (54%)
		C2H2 Zn finger	288..309	CDD:275368	8/47 (17%)
		C2H2 Zn finger	317..337	CDD:275368	5/19 (26%)
		C2H2 Zn finger	345..365	CDD:275368	6/19 (32%)
		C2H2 Zn finger	373..391	CDD:275368	5/17 (29%)
GZF1	NP_001303941.1	BTB	21..133	CDD:306997
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	153..220
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..312
		C2H2 Zn finger	319..339	CDD:275368
		C2H2 Zn finger	350..371	CDD:275368
		COG5048	<405..593	CDD:227381	51/155 (33%)
		C2H2 Zn finger	409..429	CDD:275368
		C2H2 Zn finger	437..457	CDD:275368	8/19 (42%)
		C2H2 Zn finger	465..485	CDD:275368	8/19 (42%)
		C2H2 Zn finger	493..513	CDD:275368	0/19 (0%)
		C2H2 Zn finger	521..541	CDD:275368	5/19 (26%)
		C2H2 Zn finger	549..569	CDD:275368	6/19 (32%)
		C2H2 Zn finger	577..597	CDD:275368	5/17 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050