DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and ZNF350

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	XP_016882583.1	Gene:	ZNF350 / 59348	HGNCID:	16656	Length:	574	Species:	Homo sapiens

Alignment Length:	282	Identity:	81/282 - (28%)
Similarity:	124/282 - (43%)	Gaps:	42/282 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 DSQDVESLISSVQKE----LESICNDDSNSDN------NDYMEPQNGSYFN-------------- 195
            |...|:.::..:|.|    ....|::....:|      :.::..||...|:
Human   122 DIWKVDHVLERLQSESLVNRRKPCHEHDAFENIVHCSKSQFLLGQNHDIFDLRGKSLKSNLTLVN 186

  Fly   196 -----ETINEYEVSSNPNTPLPESKSAAGRSTK-PATTK-PKRKKQYVTWKNMTEEQIIERKRLQ 253
                 |..|..|.:.|.::.|..:......:.| ||:.| ...|.|:::.|:        :|..:
Human   187 QSKGYEIKNSVEFTGNGDSFLHANHERLHTAIKFPASQKLISTKSQFISPKH--------QKTRK 243

  Fly   254 RKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCR 318
            .::..||.:||:.|..:|....|.:.|||.|...|..|.|.|....::|.||| .|.|||||:|.
Human   244 LEKHHVCSECGKAFIKKSWLTDHQVMHTGEKPHRCSLCEKAFSRKFMLTEHQR-THTGEKPYECP 307

  Fly   319 FCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRN 383
            .|.|:|...:...||::|||..|||.|..|.|.|........|:.||||.:.:.|..|.:.|.:.
Human   308 ECGKAFLKKSRLNIHQKTHTGEKPYICSECGKGFIQKGNLIVHQRIHTGEKPYICNECGKGFIQK 372

  Fly   384 THLKAHLRSKFHTAKAKTIGAE 405
            |.|.||.|  |||.|...:.:|
Human   373 TCLIAHQR--FHTGKTPFVCSE 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	6/19 (32%)
		zf-H2C2_2	272..297	CDD:290200	9/24 (38%)
		C2H2 Zn finger	288..309	CDD:275368	8/20 (40%)
		C2H2 Zn finger	317..337	CDD:275368	6/19 (32%)
		C2H2 Zn finger	345..365	CDD:275368	5/19 (26%)
		C2H2 Zn finger	373..391	CDD:275368	7/17 (41%)
ZNF350	XP_016882583.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050