DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and ZNF302

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	XP_016882467.1	Gene:	ZNF302 / 55900	HGNCID:	13848	Length:	444	Species:	Homo sapiens

Alignment Length:	342	Identity:	96/342 - (28%)
Similarity:	148/342 - (43%)	Gaps:	53/342 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 GEV---DEYIVESPEEVLDHDS---DAHHDLDEDNY--IDSVEDVDALQDMAEVAEEDSQDVESL 162
            |:|   |..|..|.||....||   |.:.|:...||  :.||..:...:....:..||.::...:
Human    46 GDVTFSDVAIDFSHEEWACLDSAQRDLYKDVMVQNYENLVSVAGLSVTKPYVIMLLEDGKEPWMM 110

  Fly   163 ISSVQKELESICNDDSNSDNNDYME---PQNGSYFNETINEYEVSSNPNTPLPESKSAAGRST-- 222
            ...:.|:.||...:...|...|..:   ||..:........||. ||.|..|..::....|||
Human   111 EKKLSKDWESRWENKELSTKKDIYDEDSPQPVTMEKVVKQSYEF-SNSNKNLEYTECDTFRSTFH 174

  Fly   223 -KPATTKPKRK-------KQYVTWKNMTEEQIIERKRL--------------------------- 252
             |...::|:..       |..:..||::::.:|:.:|:
Human   175 SKSTLSEPQNNSAEGNSHKYDILKKNLSKKSVIKSERINGGKKLLNSNKSGAAFNQSKSLTLPQT 239

  Fly   253 -QRKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYD 316
             .|::...|.:||:.|..||....|...|||.|.:.|::|||.|.....:|.|| |.|.|||||.
Human   240 CNREKIYTCSECGKAFGKQSILSRHWRIHTGEKPYECRECGKTFSHGSSLTRHQ-ISHSGEKPYK 303

  Fly   317 CRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQ 381
            |..|.|:|.:.::...|:.|||..|||.|.:|.|.|...|...:|..|||..:.:.|.||.::|.
Human   304 CIECGKAFSHGSSLTNHQSTHTGEKPYECMNCGKSFSRVSLLIQHLRIHTQEKRYECRICGKAFI 368

  Fly   382 RNTHLKAHLRSKFHTAK 398
            .::.|..|.:|  ||.:
Human   369 HSSSLIHHQKS--HTGE 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	7/19 (37%)
		zf-H2C2_2	272..297	CDD:290200	10/24 (42%)
		C2H2 Zn finger	288..309	CDD:275368	9/20 (45%)
		C2H2 Zn finger	317..337	CDD:275368	5/19 (26%)
		C2H2 Zn finger	345..365	CDD:275368	6/19 (32%)
		C2H2 Zn finger	373..391	CDD:275368	6/17 (35%)
ZNF302	XP_016882467.1	KRAB	48..109	CDD:214630	16/60 (27%)
		COG5048	<151..393	CDD:227381	72/237 (30%)
		C2H2 Zn finger	248..268	CDD:275368	7/19 (37%)
		C2H2 Zn finger	276..296	CDD:275368	9/20 (45%)
		C2H2 Zn finger	304..324	CDD:275368	5/19 (26%)
		C2H2 Zn finger	332..352	CDD:275368	6/19 (32%)
		C2H2 Zn finger	360..380	CDD:275368	7/21 (33%)
		C2H2 Zn finger	388..408	CDD:275368
		C2H2 Zn finger	416..436	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050