DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and ZNF562

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001123503.1	Gene:	ZNF562 / 54811	HGNCID:	25950	Length:	426	Species:	Homo sapiens

Alignment Length:	204	Identity:	64/204 - (31%)
Similarity:	95/204 - (46%)	Gaps:	10/204 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 GSYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKR-KKQYVTWKNMTEEQIIERKRLQR 254
            |.:..|.:.|::......|.....|......|...:.|.|. .|.:..:..::    ...|..:.
Human   224 GIHIGEKLCEFQECERAITTSSHLKQCVAVHTGKKSEKTKNCGKSFTNFSQLS----AHAKTHKG 284

  Fly   255 KRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRF 319
            ::...|::|||.|.:.|:|.:|:..|||.|...|.:|||.|.....:|.|.| .|.|.|||:|:.
Human   285 EKSFECKECGRSFRNSSSFNVHIQIHTGIKPHKCTECGKAFTRSTHLTQHVR-THTGIKPYECKE 348

  Fly   320 CTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSF---- 380
            |.::|.......||.|.||..|||.|..|.|.|..:|...:|..||||.:.:.|..|.::|
Human   349 CGQAFTQYTGLAIHIRNHTGEKPYQCKECGKAFNRSSTLTQHRRIHTGEKPYECVECGKTFITSS 413

  Fly   381 QRNTHLKAH 389
            .|:.|||.|
Human   414 HRSKHLKTH 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	8/19 (42%)
		zf-H2C2_2	272..297	CDD:290200	11/24 (46%)
		C2H2 Zn finger	288..309	CDD:275368	8/20 (40%)
		C2H2 Zn finger	317..337	CDD:275368	6/19 (32%)
		C2H2 Zn finger	345..365	CDD:275368	6/19 (32%)
		C2H2 Zn finger	373..391	CDD:275368	8/21 (38%)
ZNF562	NP_001123503.1	KRAB	40..81	CDD:307490
		COG5048	<117..308	CDD:227381	18/87 (21%)
		C2H2 Zn finger	181..198	CDD:275370
		C2H2 Zn finger	206..226	CDD:275368	1/1 (100%)
		COG5048	<258..420	CDD:227381	55/166 (33%)
		C2H2 Zn finger	263..282	CDD:275368	3/22 (14%)
		C2H2 Zn finger	290..310	CDD:275368	8/19 (42%)
		C2H2 Zn finger	318..338	CDD:275368	8/20 (40%)
		C2H2 Zn finger	346..366	CDD:275368	6/19 (32%)
		C2H2 Zn finger	374..394	CDD:275368	6/19 (32%)
		C2H2 Zn finger	402..422	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050