DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and CG14711

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_650094.1	Gene:	CG14711 / 41395	FlyBaseID:	FBgn0037922	Length:	377	Species:	Drosophila melanogaster

Alignment Length:	420	Identity:	109/420 - (25%)
Similarity:	176/420 - (41%)	Gaps:	93/420 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGSIIYNKMPKNLFHIENE-------KMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAI 62
            ||.|.:...|.........:|:       :.::::..:....|.|   :||.:|..|...|..|.
  Fly     7 CRICLTEDINSEAMAPLFDDNDAQCRELVRKIEEVGSIKLVPLQN---IPSMLCYSCVERLTSAH 68

  Fly    63 LFRERCILTQKQLVHRRRSPEAK-EPAEDVEEMASPPDCLNDPFGEVDEYIVESPEEVLDHDSDA 126
            .|||.|..:::.........|.| ||.::|      |..:.|..    |||.||
  Fly    69 KFRELCQESERTFATNVVKAEMKSEPTDEV------PHVVADNI----EYIYES----------- 112

  Fly   127 HHDLDEDNYIDSVEDVDALQDMAEVAEED-----SQDVESLISSVQKELESICNDDSNSDNNDYM 186
                 .:::||.|||...::::.|...||     ||..|:  |:|..:|          |.:|.:
  Fly   113 -----ANDFIDGVEDDIGMENIMEEPLEDGVGETSQAYET--STVVDDL----------DEDDLL 160

  Fly   187 EPQNGSYFNETINEYEVSSNPNTPLPESKSAAGRSTK----------------PATTKPKRKKQY 235
            .|      |.|.::|:       |:...:.|..|.|:                |.:...:|....
  Fly   161 VP------NSTDSDYQ-------PIERCRKAKVRKTRMTKRGRGRPRGASSGHPRSFSEERPPVQ 212

  Fly   236 VTWKNMTEEQIIERKRLQRKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHL 300
            .::|:..|..         ....:||.||..::.::...:||.||...|.|.|:.|.|.|.....
  Fly   213 ASFKSSPEVS---------STNIMCEICGNIYSKRAALNIHMRRHMAEKPFKCEICSKSFAGPSE 268

  Fly   301 MTLHQRIIHQGEKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIH 365
            :..|.| :|.||||:.|::|.:||.:.::.:.|||||||.:|::|..|.|.|..::..|.|.|.|
  Fly   269 LNRHIR-VHTGEKPFLCKYCNRSFADRSSNIRHERTHTNERPFTCSTCGKAFSYSNVLKNHMLTH 332

  Fly   366 TGVRAFACTICKQSFQRNTHLKAHLRSKFH 395
            ||.:.|.|.:|.::|.|...|..||.:..|
  Fly   333 TGEKPFLCRVCNKTFSRKHQLDQHLGTMTH 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	17/76 (22%)
		C2H2 Zn finger	260..280	CDD:275368	6/19 (32%)
		zf-H2C2_2	272..297	CDD:290200	10/24 (42%)
		C2H2 Zn finger	288..309	CDD:275368	6/20 (30%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
		C2H2 Zn finger	345..365	CDD:275368	7/19 (37%)
		C2H2 Zn finger	373..391	CDD:275368	6/17 (35%)
CG14711	NP_650094.1	zf-AD	6..81	CDD:285071	17/76 (22%)
		C2H2 Zn finger	228..248	CDD:275368	6/19 (32%)
		zf-H2C2_2	240..264	CDD:290200	9/23 (39%)
		COG5048	249..>362	CDD:227381	43/113 (38%)
		C2H2 Zn finger	256..276	CDD:275368	6/20 (30%)
		zf-H2C2_2	268..292	CDD:290200	10/24 (42%)
		C2H2 Zn finger	284..304	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	12/21 (57%)
		C2H2 Zn finger	312..332	CDD:275368	7/19 (37%)
		zf-H2C2_2	325..349	CDD:290200	10/23 (43%)
		C2H2 Zn finger	340..362	CDD:275368	7/21 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960