DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and CG6808

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001247055.1	Gene:	CG6808 / 41394	FlyBaseID:	FBgn0037921	Length:	375	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	97/428 - (22%)
Similarity:	167/428 - (39%)	Gaps:	101/428 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCI 69
            ||||.........::||.....|:|..   ..||::..|..||..||..|.:.|.:...|...|.
  Fly    10 CRTCRKKGTQSTLQSLFESNAHKLLIS---YAGTSVKPDDGLPDQICTVCLMQLEEVDRFLSACK 71

  Fly    70 LTQ---KQLVHRR-RSPEAKEPAEDVEEMASPPDCL----------NDPFG-EVDEYIVESPEE- 118
            .:.   :.||.:. .|..|.|..||.:::.......          .:|.. :..|..:|:.::
  Fly    72 QSDAHLRSLVRQTLSSASAFETLEDKDQLEQKKRARKQNISGRLIEENPINFKTQENALETTKDD 136

  Fly   119 ------------VLDHDSDAHH--DLDEDNYIDSVEDVDALQDMAE--VAEEDSQDVESLISSVQ 167
                        |.|.:.:|.:  |:.:::|  ::.|:|..:::::  .:|..||:..:...|:|
  Fly   137 EILPINKFSSDFVFDLNVNAENEKDIHQEDY--TISDMDLDREISDQNYSETYSQESSAATDSIQ 199

  Fly   168 KELESICNDDSNSDNNDYMEPQNGSYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRK 232
            :..|...|.:.::|                   |.:.             .|.:.:|
  Fly   200 ETSEDYHNLEPSAD-------------------YVID-------------LGVACEP-------- 224

  Fly   233 KQYVTWKNMTEEQIIERKRLQRKRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYT 297
                           ::.|        |:.|...:...|....|...|...|:..|:.|.|.|..
  Fly   225 ---------------DKYR--------CKICSNTYRCLSQLNAHSQVHRKEKDHQCEVCQKTFRA 266

  Fly   298 DHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHE 362
            ...:..|.| .|.|||||.|.:|::.|.:::|...|||.|||.:||:|:.|.|.|..:|.|..|.
  Fly   267 ACNLKTHMR-THTGEKPYQCCYCSRRFADNSTHRKHERLHTNERPYACNICGKTFSLSSSRNAHY 330

  Fly   363 LIHTGVRAFACTICKQSFQRNTHLKAHLRSKFHTAKAK 400
            .:|:..::..|.:||:.|:....|.||.:|..|...||
  Fly   331 YLHSSEKSHKCLMCKKEFRLKHQLTAHEKSLAHRLIAK 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	19/72 (26%)
		C2H2 Zn finger	260..280	CDD:275368	4/19 (21%)
		zf-H2C2_2	272..297	CDD:290200	7/24 (29%)
		C2H2 Zn finger	288..309	CDD:275368	6/20 (30%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
		C2H2 Zn finger	345..365	CDD:275368	7/19 (37%)
		C2H2 Zn finger	373..391	CDD:275368	7/17 (41%)
CG6808	NP_001247055.1	zf-AD	9..79	CDD:214871	19/71 (27%)
		C2H2 Zn finger	229..249	CDD:275368	4/19 (21%)
		zf-C2H2	255..277	CDD:278523	6/22 (27%)
		C2H2 Zn finger	257..277	CDD:275368	6/20 (30%)
		zf-H2C2_2	269..293	CDD:290200	10/24 (42%)
		C2H2 Zn finger	285..305	CDD:275368	7/19 (37%)
		zf-H2C2_2	299..321	CDD:290200	11/21 (52%)
		C2H2 Zn finger	313..333	CDD:275368	7/19 (37%)
		C2H2 Zn finger	341..359	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8018
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910