DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and CG31388

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	454	Identity:	122/454 - (26%)
Similarity:	189/454 - (41%)	Gaps:	85/454 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCI 69
            ||||..:....:.||||...:..:|:.|..:|...|..|.:||..:|..|..||..||.||..||
  Fly     5 CRTCSRMADPAVAKNLFDPSSSSVLRQIETLTNLQLKEDGKLPRFMCQDCQHDLQIAIDFRRVCI 69

  Fly    70 LTQKQLVHRRRSPEAKEPAEDVEEMASP--PDC------------LNDPFGEVDEYIVESPEEVL 120
            ..|:.|..:.|..|.:|  |..|.:|..  .||            |||   .:|......|::..
  Fly    70 EAQELLELQLRQVEKEE--EAFESLAEQWLDDCPDELSNLSPVLQLND---RMDFIFDPEPQDKN 129

  Fly   121 DHDSDAHHDLDEDNYIDSVEDVDALQDMAEVAEEDSQDVE----SLISSVQKELESICNDDSNS- 180
            ..:..:........|:::.:.|.:.|...|::.:.....|    .|....:.|.|:|.|.|::|
  Fly   130 TDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEAIDNRDTSSS 194

  Fly   181 ----------DNNDYMEPQNGSYFNETINEYEVSSNPNTPLPESKSAA-----GRSTKPATTK-- 228
                      :|.|.::          :::|.:...|    |::|...     |..:..|.|:
  Fly   195 HTCSKCGLEFENVDELK----------LHKYHLHDIP----PDTKFVCDHCDEGFRSAAALTRHC 245

  Fly   229 -----------PKRKKQYVTWKNMTEEQIIERKRLQR-----KRECVCEQCGRQFTDQSNFKLHM 277
                       .|.|.|:       ...|:.....||     ..:.||..||:..|...|.|.|:
  Fly   246 NMINLPLTHSCTKCKSQF-------HNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHL 303

  Fly   278 LRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRF-CTKSFHNSNTRLIHERTHTNA- 340
            :||.|.:...|.||...|||...:..||: .|..|:||.||: |.|:|...:.|.:|||.|.:|
  Fly   304 VRHAGTRRHKCDQCSASFYTAAELCSHQK-THTTERPYICRYNCGKTFRFCSARSMHERVHMDAS 367

  Fly   341 -KPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHLRSKFH---TAKAK 400
             :.|.|.:|.|.:.:.|..:.|:..|...|...|.||:.||:...|.::||:|..|   .|:||
  Fly   368 KRIYQCEYCPKSYVTPSECRTHQKYHNLTRDHGCEICRISFKTAKHYRSHLKSNAHKTLEARAK 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	26/69 (38%)
		C2H2 Zn finger	260..280	CDD:275368	7/19 (37%)
		zf-H2C2_2	272..297	CDD:290200	10/24 (42%)
		C2H2 Zn finger	288..309	CDD:275368	8/20 (40%)
		C2H2 Zn finger	317..337	CDD:275368	9/20 (45%)
		C2H2 Zn finger	345..365	CDD:275368	5/19 (26%)
		C2H2 Zn finger	373..391	CDD:275368	7/17 (41%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071	26/70 (37%)
		C2H2 Zn finger	228..254	CDD:275368	3/25 (12%)
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	8/20 (40%)
		C2H2 Zn finger	342..363	CDD:275368	9/20 (45%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..419	CDD:275368	7/17 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I1804
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.960