DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and CG8159

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_649823.2	Gene:	CG8159 / 41040	FlyBaseID:	FBgn0037619	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	117/397 - (29%)
Similarity:	176/397 - (44%)	Gaps:	80/397 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGSIIYNKMPKNLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRERCI 69
            ||.|.|...|.....||:....|:||.|||:||..|..:|.||..:|..|..||..||.||:||:
  Fly     6 CRVCASSTDNSKSLKLFNSGACKVLQQINLLTGVLLQCEPGLPDWMCETCQTDLKSAISFRDRCL 70

  Fly    70 LTQKQLVHRRRSPEAKEPAEDVEEMASPPDCLNDPFGEVDEYIVESPEEVLDHDSDAHHDLDEDN 134
            .:||..                                 :|.:|.:               :||.
  Fly    71 RSQKIF---------------------------------EESLVRN---------------EEDT 87

  Fly   135 YIDSVEDVDALQDMAEVAEEDSQDVESLISSVQKELESICNDDSNSDNNDYMEPQNGSYFNETIN 199
            :..||.  .:.:...:..|:.:....:....|..:|||:.|.|...|..|:::.     .||...
  Fly    88 FRSSVR--RSARSQRQRHEDTAPKTPASPLEVMIKLESLSNGDEEDDGIDHLDS-----CNEADM 145

  Fly   200 EYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIERKRLQRKRECV----- 259
            |..:           |:.:..:....||.|.|.|:       |..:.:::......|..|
  Fly   146 ELAI-----------KAMSSSTEDDGTTSPVRLKR-------TRRRGLKKGGKGENRTKVTLPVF 192

  Fly   260 -CEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKS 323
             |:|||...|.:|:|..|:.:|:|.:.|.|:.|..||.:...:..|| ::|.|::.:.||:|.::
  Fly   193 FCDQCGNNITGKSSFDRHLRKHSGIRPFQCELCPARFLSSGELKGHQ-VMHTGDRKFQCRYCDRT 256

  Fly   324 FHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKA 388
            :.|.:.||.|||||||.:|:.|..|.|.|.::...|.|.|||||.|.|.|.:|.:||.|.||||.
  Fly   257 YVNYSGRLRHERTHTNDRPFICAQCGKSFTNSYILKNHMLIHTGERLFRCELCHRSFARPTHLKT 321

  Fly   389 HLRSKFH 395
            |.||..|
  Fly   322 HFRSNTH 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	31/69 (45%)
		C2H2 Zn finger	260..280	CDD:275368	8/19 (42%)
		zf-H2C2_2	272..297	CDD:290200	9/24 (38%)
		C2H2 Zn finger	288..309	CDD:275368	6/20 (30%)
		C2H2 Zn finger	317..337	CDD:275368	9/19 (47%)
		C2H2 Zn finger	345..365	CDD:275368	7/19 (37%)
		C2H2 Zn finger	373..391	CDD:275368	10/17 (59%)
CG8159	NP_649823.2	zf-AD	5..78	CDD:214871	31/104 (30%)
		C2H2 Zn finger	194..214	CDD:275368	8/19 (42%)
		COG5048	<197..322	CDD:227381	53/125 (42%)
		zf-H2C2_2	206..231	CDD:290200	9/24 (38%)
		C2H2 Zn finger	222..242	CDD:275368	6/20 (30%)
		C2H2 Zn finger	250..270	CDD:275368	9/19 (47%)
		zf-H2C2_2	265..287	CDD:290200	12/21 (57%)
		C2H2 Zn finger	278..298	CDD:275368	7/19 (37%)
		zf-H2C2_2	291..315	CDD:290200	13/23 (57%)
		C2H2 Zn finger	306..328	CDD:275368	12/21 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.860