DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZNF773

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_940944.1 Gene:ZNF773 / 374928 HGNCID:30487 Length:442 Species:Homo sapiens


Alignment Length:279 Identity:78/279 - (27%)
Similarity:117/279 - (41%) Gaps:51/279 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   149 AEVAEEDSQDVESLISSVQKELESICNDDSNSDNNDYMEPQNGSYFNETINEYEVSSNPNTPLPE 213
            ||.|.|.|..||...|:||:..:..|.:..       ::.|.|.                  :|.
Human    95 AEAAAEQSASVEVPSSNVQQHQKQHCGEKP-------LKRQEGR------------------VPV 134

  Fly   214 SKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQII------ERKRLQR------KRECVCEQCGRQ 266
            .:|.....::.:....:..|..:|...:.:.|:.      .|....|      ||...|.:||:.
Human   135 LRSCRVHLSEKSLQSREVGKDLLTSSGVLKHQVTHTGEKSHRSSKSREAFHAGKRHYKCSECGKA 199

  Fly   267 FTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNTRL 331
            |..:.....|...|||.|.:.|.:|||.|.....:.:|| |:|.||:||.|..|.|||..:...:
Human   200 FGQKYLLVQHQRLHTGEKPYECSECGKLFSHKSNLFIHQ-IVHTGERPYGCSDCGKSFSRNADLI 263

  Fly   332 IHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHLR----- 391
            .|:|.||..||::|..|.|.|:..|...:|..||||||.:.|:.|.:.|..|:.|..|.|     
Human   264 QHQRVHTGEKPFTCSECGKAFRHNSTLVQHHRIHTGVRPYECSECGKLFSFNSSLMKHQRVHTGE 328

  Fly   392 --------SKFHTAKAKTI 402
                    .||::.|:..|
Human   329 RPYKCSECGKFYSHKSSLI 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871
C2H2 Zn finger 260..280 CDD:275368 5/19 (26%)
zf-H2C2_2 272..297 CDD:290200 10/24 (42%)
C2H2 Zn finger 288..309 CDD:275368 8/20 (40%)
C2H2 Zn finger 317..337 CDD:275368 7/19 (37%)
C2H2 Zn finger 345..365 CDD:275368 6/19 (32%)
C2H2 Zn finger 373..391 CDD:275368 6/17 (35%)
ZNF773NP_940944.1 KRAB 15..75 CDD:214630
KRAB 15..54 CDD:279668
C2H2 Zn finger 153..169 CDD:275368 3/15 (20%)
C2H2 Zn finger 193..213 CDD:275368 5/19 (26%)
zf-H2C2_2 206..230 CDD:290200 10/23 (43%)
COG5048 <209..438 CDD:227381 52/140 (37%)
C2H2 Zn finger 221..241 CDD:275368 8/20 (40%)
C2H2 Zn finger 249..269 CDD:275368 7/19 (37%)
zf-H2C2_2 261..286 CDD:290200 10/24 (42%)
C2H2 Zn finger 277..297 CDD:275368 6/19 (32%)
C2H2 Zn finger 305..325 CDD:275368 7/19 (37%)
zf-H2C2_2 317..342 CDD:290200 5/24 (21%)
C2H2 Zn finger 333..353 CDD:275368 4/15 (27%)
C2H2 Zn finger 361..381 CDD:275368
zf-H2C2_2 373..397 CDD:290200
C2H2 Zn finger 389..409 CDD:275368
zf-H2C2_2 401..426 CDD:290200
C2H2 Zn finger 417..437 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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