DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZSCAN22

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_001308045.1 Gene:ZSCAN22 / 342945 HGNCID:4929 Length:491 Species:Homo sapiens


Alignment Length:387 Identity:95/387 - (24%)
Similarity:157/387 - (40%) Gaps:95/387 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    75 LVHRRR------SPEAKEPAEDVEEM-------ASPPDCLNDPFGEVDEYI-VESP---EEVLDH 122
            |.|.|.      .|||....:.:|.:       |.||        |:..:: .:||   ||....
Human    67 LAHLRALCCQWLQPEAHSKEQILELLVLEQFLGALPP--------EIQAWVGAQSPKSGEEAAVL 123

  Fly   123 DSDAHHDLDEDNYIDSVEDVDALQDMAEVAEEDSQDV-ESLISSVQ--KELESICNDDSNSDNND 184
            ..|....||:..:....|..:|....:::.|.:..:| |:|:..|.  ......|..:.:|:.:.
Human   124 VEDLTQVLDKRGWDPGAEPTEASCKQSDLGESEPSNVTETLMGGVSLGPAFVKACEPEGSSERSG 188

  Fly   185 YMEPQNGSYFNETINE---YEVSSNPNTPLPES----KSAAGRSTKPATTKPKRKKQYVTWKNMT 242
            .    :|..:.:::.:   ::.:|.|...:|..    :|.|.|::..|            |.|:|
Human   189 L----SGEIWTKSVTQQIHFKKTSGPYKDVPTDQRGRESGASRNSSSA------------WPNLT 237

  Fly   243 EEQ---------IIER-----------KRLQRKREC-----------------------VCEQCG 264
            .::         :::.           ||..:.|||                       .|.:||
Human   238 SQEKPPSEDKFDLVDAYGTEPPYTYSGKRSSKCRECRKMFQSASALEAHQKTHSRKTPYACSECG 302

  Fly   265 RQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNT 329
            :.|:..::...|.:.|||.|...|::|||.|.....:|.||| ||.|||||.|..|.|:|..|..
Human   303 KAFSRSTHLAQHQVVHTGAKPHECKECGKAFSRVTHLTQHQR-IHTGEKPYKCGECGKTFSRSTH 366

  Fly   330 RLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHLR 391
            ...|:|.||..:||.|..|.|.|..::...:|:.||||.:.:.|..|.::|...:.|..|||
Human   367 LTQHQRVHTGERPYECDACGKAFSQSTHLTQHQRIHTGEKPYKCDACGRAFSDCSALIRHLR 428

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871 95/387 (25%)
C2H2 Zn finger 260..280 CDD:275368 5/19 (26%)
zf-H2C2_2 272..297 CDD:290200 10/24 (42%)
C2H2 Zn finger 288..309 CDD:275368 9/20 (45%)
C2H2 Zn finger 317..337 CDD:275368 7/19 (37%)
C2H2 Zn finger 345..365 CDD:275368 5/19 (26%)
C2H2 Zn finger 373..391 CDD:275368 5/17 (29%)
ZSCAN22NP_001308045.1 SCAN 45..133 CDD:307924 17/73 (23%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 134..161 3/26 (12%)
COG5048 <174..482 CDD:227381 70/272 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 204..249 10/56 (18%)
C2H2 Zn finger 270..290 CDD:275368 3/19 (16%)
C2H2 Zn finger 298..318 CDD:275368 5/19 (26%)
C2H2 Zn finger 326..346 CDD:275368 9/20 (45%)
C2H2 Zn finger 354..374 CDD:275368 7/19 (37%)
C2H2 Zn finger 382..402 CDD:275368 5/19 (26%)
C2H2 Zn finger 410..430 CDD:275368 7/19 (37%)
C2H2 Zn finger 438..458 CDD:275368
C2H2 Zn finger 466..486 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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