DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG18764 and CG31441

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	399	Identity:	115/399 - (28%)
Similarity:	185/399 - (46%)	Gaps:	71/399 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CRTCGSIIYNKMPK--NLFHIENEKMLQDINLVTGTTLHNDPELPSSICACCTLDLNQAILFRER 67
            |||||..:.|...:  .||:..|...:..:..:|...|..|..||..||.||.:.|::.:.||.:
  Fly     8 CRTCGKNVTNLQGRATKLFNKSNYHFISILENITDMYLEFDTTLPHLICQCCKVQLDRILTFRNK 72

  Fly    68 CILTQKQLVHRRRSPEAKEPAEDVEEMASPPDCLNDPFGEVDEYIVESPEEVLDHDSDAHHDLDE 132
            |:...|..:...|....|:..  |:|....||            :.:..:::.||       .|:
  Fly    73 CLEVHKSFMAANRKLLRKKAI--VDEELDKPD------------VEKLQQDLWDH-------TDQ 116

  Fly   133 DNYIDSVEDVDALQDMAEVAEEDSQDVESLISSVQKELESICNDDSNSDNNDYMEPQNGSYFNET 197
            :..:       |:.|.|.:..||..|.|.     .|:.|....::.|.:....::.:...:..|.
  Fly   117 EMCV-------AMADTAGLLREDHNDNEK-----AKDAEDATQNEKNQEEQVQVQTEEVEHCQEQ 169

  Fly   198 INEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIERKRLQRKRECVCEQ 262
            ::...:.         ||..:.|       .|||.|                   :..:...|:|
  Fly   170 LHNMSII---------SKGVSAR-------VPKRTK-------------------RNSKSWFCDQ 199

  Fly   263 CGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNS 327
            ||..|...:..|||:.||:|:|.|||..|..::|||:.|..| ||:|...:||.||||:|::...
  Fly   200 CGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYTDNEMRRH-RILHTDARPYACRFCSKTYRGC 263

  Fly   328 NTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRNTHLKAHLRS 392
            :::::|||||||.:|:.|.||||.|.|.|.|::||::||..|.:.|.||.|.|.|::||..|..:
  Fly   264 SSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEMLHTNQRKYHCEICDQWFLRSSHLTLHQST 328

  Fly   393 KFHTAKAKT 401
            |.|..:|::
  Fly   329 KLHQRRAES 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871	23/71 (32%)
		C2H2 Zn finger	260..280	CDD:275368	8/19 (42%)
		zf-H2C2_2	272..297	CDD:290200	11/24 (46%)
		C2H2 Zn finger	288..309	CDD:275368	9/20 (45%)
		C2H2 Zn finger	317..337	CDD:275368	8/19 (42%)
		C2H2 Zn finger	345..365	CDD:275368	11/19 (58%)
		C2H2 Zn finger	373..391	CDD:275368	9/17 (53%)
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	23/73 (32%)
		COG5048	<174..337	CDD:227381	72/198 (36%)
		C2H2 Zn finger	197..217	CDD:275370	8/19 (42%)
		C2H2 Zn finger	225..245	CDD:275368	9/20 (45%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		zf-H2C2_2	268..290	CDD:290200	14/21 (67%)
		C2H2 Zn finger	281..301	CDD:275368	11/19 (58%)
		C2H2 Zn finger	309..328	CDD:275368	9/18 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I19075
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2531
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000724
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_120097
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950