DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and ZSCAN1

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	XP_006723212.1	Gene:	ZSCAN1 / 284312	HGNCID:	23712	Length:	448	Species:	Homo sapiens

Alignment Length:	320	Identity:	70/320 - (21%)
Similarity:	110/320 - (34%)	Gaps:	101/320 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 IDSVEDVDALQDMAEVAEEDSQDVESLISSVQKE--------LESICNDDSNSDNNDYMEPQNGS 192
            :||||.    ||.:...|||.:...|     |||        |:::....:..:.::::|.....
Human   168 LDSVEP----QDWSFGEEEDGKSPRS-----QKEPSQASELILDAVAAAPALPEESEWLETTQLQ 223

  Fly   193 YFNETINEYE-------VSSNPNTPL-------PE----SKSAAGRSTKPATTKPKRKKQYVTWK 239
            ....|..|.|       :.|....||       ||    ..|:..|:.....:.|         |
Human   224 QSLHTRAEAEAPRAPGLLGSRARLPLKPSIWDEPEDLLAGPSSDLRAEGTVISSP---------K 279

  Fly   240 NMTEEQIIERKRLQRKRECVCEQCGRQFTDQSNFKLHMLRHT-------------------GNKN 285
            ..:.::|..|:|             .:.||||......|:||                   |.:.
Human   280 GPSAQRISPRRR-------------NRNTDQSGRHQPSLKHTKGGTQEAVAGISVVPRGPRGGRP 331

  Fly   286 FACQQCGKRF-YTDHLMTLHQRIIHQGEKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCD 349
            |.|..||..| :..|.:. ||: .|:.|.|:.|..|.|.|.:::....|.:.|....|..
Human   332 FQCADCGMVFTWVTHFIE-HQK-THREEGPFPCPECGKVFLHNSVLTEHGKIHLLEPPRK----- 389

  Fly   350 KCFKSASGRKRHELI------------HTGVRAFACTICKQSFQRNTHLKAHLRSKFHTA 397
               |:...:...|.:            .:..|.|.|::|.::|....||..|  .|.|||
Human   390 ---KAPRSKGPRESVPPRDGAQGPVAPRSPKRPFQCSVCGKAFPWMVHLIDH--QKLHTA 444

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	5/19 (26%)
		zf-H2C2_2	272..297	CDD:290200	9/44 (20%)
		C2H2 Zn finger	288..309	CDD:275368	7/21 (33%)
		C2H2 Zn finger	317..337	CDD:275368	5/19 (26%)
		C2H2 Zn finger	345..365	CDD:275368	2/31 (6%)
		C2H2 Zn finger	373..391	CDD:275368	6/17 (35%)
ZSCAN1	XP_006723212.1	SCAN	75..162	CDD:280241
		C2H2 Zn finger	334..354	CDD:275368	7/21 (33%)
		zf-H2C2_2	346..371	CDD:290200	10/26 (38%)
		C2H2 Zn finger	362..382	CDD:275368	5/19 (26%)
		C2H2 Zn finger	422..442	CDD:275368	7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050