DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZNF396

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_001309215.1 Gene:ZNF396 / 252884 HGNCID:18824 Length:335 Species:Homo sapiens


Alignment Length:323 Identity:80/323 - (24%)
Similarity:115/323 - (35%) Gaps:94/323 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 VESPEEVLDHDSDAH-----------HDLDEDNYIDSVEDVDALQDMAEVA------EEDSQD-- 158
            :|..|:..|.||..|           ....:..|.||....:||..:.|:.      |..:::  
Human    27 MEEEEQTCDPDSSLHWSSSYSPETFRQQFRQFGYQDSPGPHEALSRLWELCHLWLRPEVHTKEQI 91

  Fly   159 -----VESLISSVQKELESICNDDSNSDNNDYMEPQNGSYFNETINEYE-VSSNPNTP------- 210
                 :|..::.:.|||::.....         .|:||   .||:...| |....:.|       
Human    92 LELLVLEQFLAILPKELQAWVQKH---------HPENG---EETVTMLEDVERELDGPKQIFFGR 144

  Fly   211 ---LPESKSAAGRSTKPATTKP----KRKKQYVTWK-----------NMTEEQIIERKRLQRKRE 257
               :...|.|....|:...:..    |::.|..:|:           ..|..:...|::.....|
Human   145 RKDMIAEKLAPSEITEELPSSQLMPVKKQLQGASWELQSLRPHDEDIKTTNVKSASRQKTSLGIE 209

  Fly   258 CVC--------------------EQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMT 302
            ..|                    ||.||....|.|       .:..|...|.:|||.|.....:.
Human   210 LHCNVSNILHMNGSQSSTYRGTYEQDGRFEKRQGN-------PSWKKQQKCDECGKIFSQSSALI 267

  Fly   303 LHQRIIHQGEKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASG----RKRH 361
            |||| ||.|:|||.|..|.|:|..|...:.|.||||..|||.||.|.|.|..:|.    ||||
Human   268 LHQR-IHSGKKPYACDECAKAFSRSAILIQHRRTHTGEKPYKCHDCGKAFSQSSNLFRHRKRH 329

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871
C2H2 Zn finger 260..280 CDD:275368 7/39 (18%)
zf-H2C2_2 272..297 CDD:290200 7/24 (29%)
C2H2 Zn finger 288..309 CDD:275368 9/20 (45%)
C2H2 Zn finger 317..337 CDD:275368 7/19 (37%)
C2H2 Zn finger 345..365 CDD:275368 10/21 (48%)
C2H2 Zn finger 373..391 CDD:275368
ZNF396NP_001309215.1 SCAN 48..157 CDD:128708 21/120 (18%)
SCAN 48..136 CDD:280241 18/99 (18%)
COG5048 239..>306 CDD:227381 28/74 (38%)
zf-C2H2 252..273 CDD:278523 9/21 (43%)
C2H2 Zn finger 253..273 CDD:275368 9/20 (45%)
zf-H2C2_2 269..290 CDD:290200 13/21 (62%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
zf-H2C2_2 294..318 CDD:290200 13/23 (57%)
C2H2 Zn finger 309..329 CDD:275368 8/19 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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