DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18764 and ZSCAN23

DIOPT Version :9

Sequence 1:NP_652712.2 Gene:CG18764 / 59239 FlyBaseID:FBgn0042205 Length:409 Species:Drosophila melanogaster
Sequence 2:NP_001012458.1 Gene:ZSCAN23 / 222696 HGNCID:21193 Length:389 Species:Homo sapiens


Alignment Length:337 Identity:93/337 - (27%)
Similarity:140/337 - (41%) Gaps:81/337 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 RRRSPEAKEPA----EDVE-EMASPPDCLNDPFGEVDEYIVE--SPEEVLDHDSDAHHDLDED-- 133
            |:..|.:.|.|    ||:| |:..|.:.:.....|.:|::.|  :|....:..:|....|:|.  
Human   109 RQHRPVSGEEAVTVLEDLERELDDPGEQVLSHAHEQEEFVKEKATPGAAQESSNDQFQTLEEQLG 173

  Fly   134 ---NYIDSVEDVDALQDM--AEVA--EEDSQDVESLISSVQKELESICNDDSNSDNNDYMEPQNG 191
               ..:..|:::|.....  .|:|  .|.||:|:|||..:.|                    |||
Human   174 YNLREVCPVQEIDGKAGTWNVELAPKREISQEVKSLIQVLGK--------------------QNG 218

  Fly   192 SYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIERKRLQR-- 254
            :.               |.:||......|                       |..:|::|:..  
Human   219 NI---------------TQIPEYGDTCDR-----------------------EGRLEKQRVSSSV 245

  Fly   255 KRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIHQGEKPYDCRF 319
            :|..:|.:||:.||..|....|...|||.|.:.|.:||:.|.....:..||| :|.|||.|.|..
Human   246 ERPYICSECGKSFTQNSILIEHQRTHTGEKPYECDECGRAFSQRSGLFQHQR-LHTGEKRYQCSV 309

  Fly   320 CTKSFHNSNTRLIHE-RTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSFQRN 383
            |.|:| :.|..|.|. |.||..|||.|:.|:|.|...|...:|:.||||.|.:.|..|.::|..:
Human   310 CGKAF-SQNAGLFHHLRIHTGEKPYQCNQCNKSFSRRSVLIKHQRIHTGERPYECEECGKNFIYH 373

  Fly   384 THLKAHLRSKFH 395
            .:|..|  .|.|
Human   374 CNLIQH--RKVH 383

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18764NP_652712.2 zf-AD 4..75 CDD:214871
C2H2 Zn finger 260..280 CDD:275368 7/19 (37%)
zf-H2C2_2 272..297 CDD:290200 9/24 (38%)
C2H2 Zn finger 288..309 CDD:275368 7/20 (35%)
C2H2 Zn finger 317..337 CDD:275368 8/20 (40%)
C2H2 Zn finger 345..365 CDD:275368 6/19 (32%)
C2H2 Zn finger 373..391 CDD:275368 5/17 (29%)
ZSCAN23NP_001012458.1 SCAN 44..156 CDD:128708 13/46 (28%)
SCAN 45..132 CDD:280241 8/22 (36%)
COG5048 <215..384 CDD:227381 66/231 (29%)
zf-C2H2 249..271 CDD:278523 7/21 (33%)
C2H2 Zn finger 251..271 CDD:275368 7/19 (37%)
zf-H2C2_2 264..288 CDD:290200 9/23 (39%)
C2H2 Zn finger 279..299 CDD:275368 7/20 (35%)
zf-H2C2_2 292..316 CDD:290200 12/25 (48%)
C2H2 Zn finger 307..327 CDD:275368 8/20 (40%)
zf-H2C2_2 323..344 CDD:290200 10/20 (50%)
C2H2 Zn finger 335..355 CDD:275368 6/19 (32%)
zf-H2C2_2 348..372 CDD:290200 9/23 (39%)
C2H2 Zn finger 363..383 CDD:275368 6/21 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 123 1.000 Inparanoid score I4733
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.960

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