DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and znf-782

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_500033.1	Gene:	znf-782 / 190310	WormBaseID:	WBGene00021931	Length:	662	Species:	Caenorhabditis elegans

Alignment Length:	351	Identity:	83/351 - (23%)
Similarity:	125/351 - (35%)	Gaps:	95/351 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   125 DAHHDLDEDNYIDSVEDVDALQDMAEVAEEDSQDVESLISSVQKELESICNDDSNSDNNDYMEP- 188
            |.|....|:...:..||        |:.||:.:        ..:|||.:.|.||.|.......|
Worm    18 DIHMKDPEEEEFEEYED--------ELLEEEEE--------FDEELEELENSDSASSLVSAGSPH 66

  Fly   189 ----QNGSYFNETINEYEVSSNPNTPLPESKSAAGRSTKPATTKPKRKKQYVTWKNMTEEQIIER 249
                .|||:          .|:|...:......:|.|..|.....||....|..|..:...|:|.
Worm    67 GSSSSNGSH----------GSSPPLQVQSPSQGSGSSGSPTGQPEKRHICTVCGKGFSYFSILES 121

  Fly   250 KRLQR--KRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRIIH--- 309
            .:...  ::...|..|.:.|..::..::|...|||.:.:.|:.|.|.|......|:|::..|
Worm   122 HKRSHTGEKPYNCHFCQKTFAQKATLQVHERTHTGERPYKCRYCEKTFAQYGTKTVHEKSAHLGI 186

  Fly   310 ------------------------QGEKPYDCRFCTKSF-------------HNSNTR------- 330
                                    .|:|.:.|.||.|:|             |..|.|
Worm   187 RNYKCPKCDKLLSSPSALYTHKKTHGDKTFRCDFCPKTFALKNYLKLHVKQVHEQNERKHVCVYC 251

  Fly   331 ----------LIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFACTICKQSF----Q 381
                      .:|.||||..:||.|..|.|.|.|....:.||..|||.|.::|..|:::|    |
Worm   252 NKGFAYAGSLQVHVRTHTGERPYVCKFCPKAFASQGNLQSHERTHTGERPYSCQFCQRTFIQKSQ 316

  Fly   382 RNTHLKAHLRSKFHTAKAKTIGAEVL 407
            ...|...||..| |:....:..|::|
Worm   317 LTAHESTHLTQK-HSVNPDSTTADIL 341

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	4/19 (21%)
		zf-H2C2_2	272..297	CDD:290200	8/24 (33%)
		C2H2 Zn finger	288..309	CDD:275368	6/20 (30%)
		C2H2 Zn finger	317..337	CDD:275368	10/49 (20%)
		C2H2 Zn finger	345..365	CDD:275368	7/19 (37%)
		C2H2 Zn finger	373..391	CDD:275368	6/21 (29%)
znf-782	NP_500033.1	C2H2 Zn finger	106..126	CDD:275368	4/19 (21%)
		zf-H2C2_2	119..143	CDD:290200	4/23 (17%)
		C2H2 Zn finger	134..154	CDD:275368	4/19 (21%)
		zf-H2C2_2	147..171	CDD:290200	8/23 (35%)
		C2H2 Zn finger	162..180	CDD:275368	6/17 (35%)
		COG5048	<187..404	CDD:227381	39/156 (25%)
		C2H2 Zn finger	191..211	CDD:275370	0/19 (0%)
		C2H2 Zn finger	218..239	CDD:275368	5/20 (25%)
		C2H2 Zn finger	248..268	CDD:275368	2/19 (11%)
		zf-H2C2_2	260..285	CDD:290200	11/24 (46%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		zf-H2C2_2	288..313	CDD:290200	9/24 (38%)
		C2H2 Zn finger	304..324	CDD:275368	5/19 (26%)
		C2H2 Zn finger	386..403	CDD:275368
		C2H2 Zn finger	424..441	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000