DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18764 and ZNF582

DIOPT Version :9

Sequence 1:	NP_652712.2	Gene:	CG18764 / 59239	FlyBaseID:	FBgn0042205	Length:	409	Species:	Drosophila melanogaster
Sequence 2:	NP_001307300.2	Gene:	ZNF582 / 147948	HGNCID:	26421	Length:	517	Species:	Homo sapiens

Alignment Length:	155	Identity:	60/155 - (38%)
Similarity:	93/155 - (60%)	Gaps:	4/155 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   245 QIIERKRLQR-KRECVCEQCGRQFTDQSNFKLHMLRHTGNKNFACQQCGKRFYTDHLMTLHQRII 308
            |:||.:|... ::...|::||:.|...|:.|:|...|||.|.:||::|||.|.....:..|| .:
Human   269 QLIEHQRTHTGEKPYQCKECGKAFNRISHLKVHYRIHTGEKPYACKECGKTFSHRSQLIQHQ-TV 332

  Fly   309 HQGEKPYDCRFCTKSFHNSNTRLIHERTHTNAKPYSCHHCDKCFKSASGRKRHELIHTGVRAFAC 373
            |.|.|.|:|:.|.|:|:..:|.:.|:|.||..|||.|..|.|.|:.:|..|:|:.||||.:.:.|
Human   333 HTGRKLYECKECGKAFNQGSTLIRHQRIHTGEKPYECKVCGKAFRVSSQLKQHQRIHTGEKPYQC 397

  Fly   374 TICKQSFQRNTHLKAHLRSKFHTAK 398
            .:|.::|:|.:||..|.|  .||.:
Human   398 KVCGRAFKRVSHLTVHYR--IHTGE 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18764	NP_652712.2	zf-AD	4..75	CDD:214871
		C2H2 Zn finger	260..280	CDD:275368	7/19 (37%)
		zf-H2C2_2	272..297	CDD:290200	12/24 (50%)
		C2H2 Zn finger	288..309	CDD:275368	7/20 (35%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
		C2H2 Zn finger	345..365	CDD:275368	7/19 (37%)
		C2H2 Zn finger	373..391	CDD:275368	7/17 (41%)
ZNF582	NP_001307300.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4733
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960