DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and prss60.1

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001082915.1	Gene:	prss60.1 / 799770	ZFINID:	ZDB-GENE-070424-25	Length:	387	Species:	Danio rerio

Alignment Length:	282	Identity:	81/282 - (28%)
Similarity:	121/282 - (42%)	Gaps:	61/282 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SFLLLLALDFLSAGQVN-----RWEQRIIGGEPIGIEQVPWQVSLQ--YFGDHVCGGSIYSENII 62
            |..|||.:.. |..|:|     ....||:||........||||||.  .:|.|.||||:.:...:
Zfish     8 SLALLLCVQG-SHSQLNVCGLAPLNNRIVGGVNAFDGSWPWQVSLHSPIYGGHFCGGSLINSEWV 71

  Fly    63 VTAAHCFFDEEGNRLDDQGYQVRAGSALTDSNGTLV---DVAALIIHEEYAFDLNINDIAIVRLS 124
            :|||||.     .|:......|..|........|..   .|:.:.:|..|....|.||||::.||
Zfish    72 LTAAHCL-----PRITTSSLLVFLGKTTQQGVNTYEINRTVSVITVHPSYNNLTNENDIALLHLS 131

  Fly   125 TPLEFTSKVQPIPLAKTNP-YPR-SIALVSGWG------------------VSYILNDSTNLYPT 169
            :.:.|::.::|:.||..|. :|. :.:.::|||                  :..:.||..|
Zfish   132 SAVTFSNYIRPVCLAAQNSVFPNGTSSWITGWGNIQLGVNLPAPGILQETMIPVVPNDQCN---- 192

  Fly   170 HLQGLALHIKSIFSCRLFDPSLLCAGTY--GRTACHGDSGGPLVVNKQLV----GVVSWGRKGCV 228
                      ::........:::|||..  ||..|.||||||:|..:.||    |:.||| .||.
Zfish   193 ----------ALLGSGSVTNNMICAGLLQGGRDTCQGDSGGPMVSKQCLVWVQSGITSWG-YGCA 246

  Fly   229 ---SSAFFVSVPYFREWILNAI 247
               |...:..|..::.|| |:|
Zfish   247 DPYSPGVYTRVSQYQSWI-NSI 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	70/250 (28%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	69/249 (28%)
prss60.1	NP_001082915.1	Tryp_SPc	33..264	CDD:214473	70/250 (28%)
		Tryp_SPc	34..267	CDD:238113	72/253 (28%)
		Somatomedin_B	349..382	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910