DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG17234 and ST14

DIOPT Version :9

Sequence 1:NP_722785.1 Gene:CG17234 / 59225 FlyBaseID:FBgn0042187 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_068813.1 Gene:ST14 / 6768 HGNCID:11344 Length:855 Species:Homo sapiens


Alignment Length:259 Identity:81/259 - (31%)
Similarity:118/259 - (45%) Gaps:60/259 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 EQRIIGGEPIGIEQVPWQVSLQYFGD-HVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAG 87
            :.|::||......:.||||||...|. |:||.|:.|.|.:|:||||:.|:.|.|..|. .|..|.
Human   612 QARVVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDP-TQWTAF 675

  Fly    88 SALTDSNGTLVD------VAALIIH---EEYAFDLNINDIAIVRLSTPLEFTSKVQPIPLA-KTN 142
            ..|.|.:.....      :..:|.|   .::.||.   |||::.|..|.|::|.|:||.|. .::
Human   676 LGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDY---DIALLELEKPAEYSSMVRPICLPDASH 737

  Fly   143 PYPRSIAL-VSGWG-VSY--------------ILNDST--NLYPTHLQGLALHIKSIFSCRLFDP 189
            .:|...|: |:||| ..|              ::|.:|  ||.|..:                .|
Human   738 VFPAGKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQI----------------TP 786

  Fly   190 SLLCAG--TYGRTACHGDSGGPLVVNKQ-----LVGVVSWGRKGCV---SSAFFVSVPYFREWI 243
            .::|.|  :.|..:|.|||||||...:.     ..|||||| .||.   ....:..:|.||:||
Human   787 RMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWG-DGCAQRNKPGVYTRLPLFRDWI 849

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17234NP_722785.1 Tryp_SPc 26..243 CDD:214473 79/255 (31%)
Tryp_SPc 27..243 CDD:238113 78/254 (31%)
ST14NP_068813.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
SEA 88..>171 CDD:307516
CUB 227..332 CDD:238001
CUB 340..444 CDD:238001
LDLa 454..486 CDD:238060
LDLa 488..523 CDD:238060
LDLa 525..559 CDD:238060
LDLa 567..602 CDD:238060
Tryp_SPc 615..852 CDD:238113 80/256 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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