DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and PRSS56

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001356777.1	Gene:	PRSS56 / 646960	HGNCID:	39433	Length:	604	Species:	Homo sapiens

Alignment Length:	248	Identity:	69/248 - (27%)
Similarity:	105/248 - (42%)	Gaps:	29/248 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQ 80
            |...|.|...||:||........||.|.||..|..:|||.:.:.:.::||||||.......|
Human    94 STANVTRAHGRIVGGSAAPPGAWPWLVRLQLGGQPLCGGVLVAASWVLTAAHCFVGAPNELL--- 155

  Fly    81 GYQVRAGSALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPI--PLAKTNP 143
             :.|.............|.|..::.|.::......||:|:|:|.||:......:|:  |.....|
Human   156 -WTVTLAEGSRGEQAEEVPVNRILPHPKFDPRTFHNDLALVQLWTPVSPGGSARPVCLPQEPQEP 219

  Fly   144 YPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCR------LFDPSLLCAG--TYGRT 200
            ...:...::|||.  :..|...  ...::...:.:.|..:||      |...::||||  ..|..
Human   220 PAGTACAIAGWGA--LFEDGPE--AEAVREARVPLLSTDTCRRALGPGLRPSTMLCAGYLAGGVD 280

  Fly   201 ACHGDSGGPLVVNKQ-------LVGVVSWGRKGC---VSSAFFVSVPYFREWI 243
            :|.|||||||..::.       |.||.||| .||   .....:..|..|::|:
Human   281 SCQGDSGGPLTCSEPGPRPREVLFGVTSWG-DGCGEPGKPGVYTRVAVFKDWL 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	65/236 (28%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	64/235 (27%)
PRSS56	NP_001356777.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	64..96		1/1 (100%)
		Tryp_SPc	105..335	CDD:238113	65/237 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	443..475
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	574..604
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910