DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and tmprss5

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_009289870.1	Gene:	tmprss5 / 569688	ZFINID:	ZDB-GENE-131121-184	Length:	551	Species:	Danio rerio

Alignment Length:	250	Identity:	88/250 - (35%)
Similarity:	116/250 - (46%)	Gaps:	36/250 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGSAL 90
            |||||....:.:.||||||.|...|:|||||.:...|||||||.   ...||......|.....:
Zfish   311 RIIGGVEAALGRWPWQVSLYYNNRHICGGSIITNQWIVTAAHCV---HNYRLPQVPSWVVYAGII 372

  Fly    91 TDSNGTLVD-----VAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPIPLAKTNPYPRSI-- 148
            |.:...|..     |..:|.::.|....:.||||:|:|.|||.|:..::|:.|.:   |...:
Zfish   373 TSNLAKLAQYQGFAVERIIYNKNYNHRTHDNDIALVKLKTPLNFSDTIRPVCLPQ---YDHDLPG 434

  Fly   149 ---ALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSCRL-------FDPSLLCAG-TYGRT-A 201
               ..:||||  |...|.. |.|..|:...:.:.|...|..       ....:|||| :.|:. |
Zfish   435 GTQCWISGWG--YTQPDDV-LIPEVLKEAPVPLISTKKCNSSCMYNGEITSRMLCAGYSEGKVDA 496

  Fly   202 CHGDSGGPLVVNKQ----LVGVVSWGRKGCVS---SAFFVSVPYFREWILNAIAS 249
            |.||||||||...:    |||||||| .||..   ...:..|..|..||.:.|.|
Zfish   497 CQGDSGGPLVCQDENVWRLVGVVSWG-TGCAEPNHPGVYSKVAEFLGWIYDIIES 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	84/242 (35%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	83/241 (34%)
tmprss5	XP_009289870.1	SRCR_2	211..306	CDD:292133
		Tryp_SPc	311..544	CDD:214473	84/242 (35%)
		Tryp_SPc	312..547	CDD:238113	85/244 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910