DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and PROC

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_024308770.1	Gene:	PROC / 5624	HGNCID:	9451	Length:	576	Species:	Homo sapiens

Alignment Length:	266	Identity:	72/266 - (27%)
Similarity:	110/266 - (41%)	Gaps:	65/266 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 QVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDH----VCGGSIYSENIIVTAAHCFFDEEGNRLDD 79
            |.::.:.|:|.|:.......||||.|.   |.    .||..:...:.::||||| .||....|..
Human   319 QEDQVDPRLIDGKMTRRGDSPWQVVLL---DSKKKLACGAVLIHPSWVLTAAHC-MDESKKLLVR 379

  Fly    80 QG-YQVRAGSALTDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPIPLAKTNP 143
            .| |.:|........    :|:..:.:|..|:.....||||::.|:.|...:..:.||.|..:..
Human   380 LGEYDLRRWEKWELD----LDIKEVFVHPNYSKSTTDNDIALLHLAQPATLSQTIVPICLPDSGL 440

  Fly   144 YPRSI------ALVSGWGV------------SYILNDSTNLYPTHLQGLALHIK---------SI 181
            ..|.:      .||:|||.            :::||               .||         |.
Human   441 AERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLN---------------FIKIPVVPHNECSE 490

  Fly   182 FSCRLFDPSLLCAGTYG--RTACHGDSGGPLVVNKQ----LVGVVSWGRKGC---VSSAFFVSVP 237
            ....:...::||||..|  :.||.||||||:|.:..    |||:|||| :||   .:...:..|.
Human   491 VMSNMVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWG-EGCGLLHNYGVYTKVS 554

  Fly   238 YFREWI 243
            .:.:||
Human   555 RYLDWI 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	69/257 (27%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	68/256 (27%)
PROC	XP_024308770.1	GLA	117..168	CDD:214503
		EGF_CA	182..213	CDD:238011
		FXa_inhibition	255..290	CDD:317114
		Tryp_SPc	328..563	CDD:238113	70/257 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910