DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Prss53

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_006230384.1	Gene:	Prss53 / 499270	RGDID:	1566127	Length:	591	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	61/244 - (25%)
Similarity:	99/244 - (40%)	Gaps:	68/244 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGSALTDS---NGTLVDV 100
            |||.|::..|.|:|.||:.::..::||||||  |:....:...:.|..||...:.   ....|.|
  Rat    49 PWQASVRRQGVHICSGSLVADTWVLTAAHCF--EKMATAELSSWSVVLGSLKQEGLSPGAEEVGV 111

  Fly   101 AALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQPIPLAKTNPYPRSIALVSGWGVSYILNDSTN 165
            |||.:.:.|......:|:|:::|:.|:..|:...|.|   |:.:|..   .|.|...:..|.|..
  Rat   112 AALQLPKAYNHYSQGSDLALLQLTHPIVHTTLCLPQP---THHFPFG---ASCWATGWDQNTSDG 170

  Fly   166 LY-PTH------------------------------------LQGLALHIKSIFSCR-------- 185
            .| |.|                                    |:.|.|.:.|..:|.
  Rat   171 KYCPRHKSRESQTGSVLTVLALCSHCVSELDSTLSPLPVSRTLRNLRLRLISRPTCNCLYNRLHQ 235

  Fly   186 --LFDPS---LLCAGTYG--RTACHGDSGGPLVVNKQ-----LVGVVSW 222
              |.:|:   :||.|...  :..|.||||||::..:.     .||::|:
  Rat   236 RLLANPARSGMLCGGAQPGVQGPCQGDSGGPVMCREPDGHWVQVGIISF 284

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	61/244 (25%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	61/244 (25%)
Prss53	XP_006230384.1	Tryp_SPc	45..310	CDD:238113	61/244 (25%)
Prss53	XP_006230384.1	Tryp_SPc	341..561	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24276
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030