DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17234 and Tmprss11c

DIOPT Version :9

Sequence 1:	NP_722785.1	Gene:	CG17234 / 59225	FlyBaseID:	FBgn0042187	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001025468.1	Gene:	Tmprss11c / 435845	MGIID:	3521861	Length:	431	Species:	Mus musculus

Alignment Length:	236	Identity:	79/236 - (33%)
Similarity:	118/236 - (50%)	Gaps:	27/236 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFDEEGNRLDDQGYQVRAGSAL 90
            ::.||:.....:.|||.|||....|.||.::.|...::||||||.    ...:.:.::|..|..|
Mouse   199 KVAGGQDAEEGEWPWQASLQQNSVHRCGATLISNYWLITAAHCFI----RAANPKDWKVSFGFLL 259

  Fly    91 TDSNGTLVDVAALIIHEEYAFDLNINDIAIVRLSTPLEFTSKVQP--IPLAKTNPYPRSIALVSG 153
            :....... |..:||||.|::..:.||||:||||:|:.:.|.::.  :|.|.....|.|..:|:|
Mouse   260 SKPQAPRA-VKNIIIHENYSYPAHDNDIAVVRLSSPVLYESNIRRACLPEATQKFPPNSDVVVTG 323

  Fly   154 WGVSYILNDSTNLYPTHLQGLALHIKSIFSCR-------LFDPSLLCAG-TYGRT-ACHGDSGGP 209
            ||......||.|:    ||...:.|....:|.       :..|.::||| ..||. ||.||||||
Mouse   324 WGTLKSDGDSPNI----LQKGKVKIIDNKTCNSGKAYGGMITPGMMCAGFLKGRVDACQGDSGGP 384

  Fly   210 LVVNKQ-----LVGVVSWGRKGCVSS--AFFVSVPYFREWI 243
            ||....     |.|:||||.:..:.:  ..:..|.|:|:||
Mouse   385 LVSEDSKGIWFLAGIVSWGDECALPNKPGVYTRVTYYRDWI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	26..243	CDD:214473	77/234 (33%)
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	77/233 (33%)
Tmprss11c	NP_001025468.1	SEA	62..157	CDD:279699
		Tryp_SPc	199..425	CDD:214473	77/234 (33%)
		Tryp_SPc	200..428	CDD:238113	79/235 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910