DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG17234 and KLK2

DIOPT Version :9

Sequence 1:NP_722785.1 Gene:CG17234 / 59225 FlyBaseID:FBgn0042187 Length:251 Species:Drosophila melanogaster
Sequence 2:NP_005542.1 Gene:KLK2 / 3817 HGNCID:6363 Length:261 Species:Homo sapiens


Alignment Length:264 Identity:81/264 - (30%)
Similarity:119/264 - (45%) Gaps:30/264 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     7 LLLLALDFLSAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCFFD 71
            :|.:||.....|.|...:.||:||........||||::...|...|||.:.....::|||||.  
Human     5 VLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-- 67

  Fly    72 EEGNRLDDQGYQVRAGSALTDSNGTLVDVAALIIHEEYAFDL-----------NINDIAIVRLST 125
                :.:.|.:..|......:..|..|.|:....|..|...|           :.:|:.::|||.
Human    68 ----KKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSE 128

  Fly   126 PLEFTSKVQPIPLAKTNPYPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSC-RLFDP 189
            |.:.|..|:.:.|....|...:....||||   .:.....|.|..||.::||:.|...| |.:..
Human   129 PAKITDVVKVLGLPTQEPALGTTCYASGWG---SIEPEEFLRPRSLQCVSLHLLSNDMCARAYSE 190

  Fly   190 S----LLCAG--TYGRTACHGDSGGPLVVNKQLVGVVSWGRKGCV---SSAFFVSVPYFREWILN 245
            .    :||||  |.|:..|.||||||||.|..|.|:.|||.:.|.   ..|.:..|.::|:||.:
Human   191 KVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKD 255

  Fly   246 AIAS 249
            .||:
Human   256 TIAA 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG17234NP_722785.1 Tryp_SPc 26..243 CDD:214473 72/237 (30%)
Tryp_SPc 27..243 CDD:238113 71/236 (30%)
KLK2NP_005542.1 Tryp_SPc 25..256 CDD:238113 73/239 (31%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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