Protein Alignment CG17234 and KLK1

DIOPT Version :10

• Sequence 1: NP_722785.1
• Gene: CG17234 / 59225
• FlyBaseID: FBgn0042187
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 82/269 - (30%)
• Similarity: 113/269 - (42%)
• Gaps: 38/269 - (14%)

  Fly     6 FLLL-LALDFLSAGQVNRWEQRIIGGEPIGIEQVPWQVSLQYFGDHVCGGSIYSENIIVTAAHCF 69
            ||:| |||.....|.....:.||:||........|||.:|.:|....|||.:.....::|||||.
Human     3 FLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCI 67

  Fly    70 FDEEGNRLDDQGYQVRAG--SALTDSN-GTLVDVAALIIHEEYAFDLNIN-----------DIAI 120
            .|         .||:..|  :...|.| ...|.|:....|..:...|..|           |:.:
Human    68 SD---------NYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLML 123

  Fly   121 VRLSTPLE-FTSKVQPIPLAKTNPYPRSIALVSGWGVSYILNDSTNLYPTHLQGLALHIKSIFSC 184
            :||:.|.: .|..|:.:.|....|...|..|.||||.....|.|   :|..||.:.|.|.....|
Human   124 LRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSIEPENFS---FPDDLQCVDLKILPNDEC 185

  Fly   185 R-----LFDPSLLCAGTY--GRTACHGDSGGPLVVNKQLVGVVSWGRKGCVS---SAFFVSVPYF 239
            :     .....:||.|..  |:..|.|||||||:.:..|.||.|||...|.:   .:..|.|..:
Human   186 KKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSY 250

  Fly   240 REWILNAIA 248
            .:||.:.||
Human   251 VKWIEDTIA 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17234	NP_722785.1	Tryp_SPc	27..243	CDD:238113	70/240 (29%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	72/243 (30%)